Results 131 to 140 of about 224,890 (308)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Brief von Louis Spohr an Sebastian Binder

open access: yes
BRIEF VON LOUIS SPOHR AN SEBASTIAN BINDER Brief von Louis Spohr an Sebastian Binder ...
Binder, Sebastian, Spohr, Louis
core  

Preparation and characterization of starch-based binders for binder jetting

open access: yesRSC Advances
In recent years, binder jetting technology has made significant advances across industries, expanding the range of material options to meet diverse needs.
Hongtao Jiang, Xinhao Yang, Hao Wang
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

AHC interview with Ruth Martha Binder.

open access: yes, 2008
June 4, 2008Ruth Binder, née Wottitzky was born on Jan. 17, 1926 in Windigstein, Lower Austria. She and her family immigrated via Zurich, Switzerland and Paris, France and arrived in the US in April, 1939, settling in Washington, D.C. Binder went to high
Rohrbach, Philipp   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Formulation of Titanium - based Metal Feedstocks and the Fabrication of Parts using the Powder Injection Moulding Process

open access: yes, 2015
Development of a profitable titanium industry for New Zealand will not come about without innovative technologies. Plastic injection moulding has long held a place in NZ manufacturing to produce large quantities of complex parts and holds the key to such
Ewart, Paul Douglas
core  

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