Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Photovoltaic Effect in (PbCrO4-HgO) Binder Layer
Meenu Sachan +12 more
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Correction: Binder Jetting of Hydroxyapatite/Carboxymethyl Chitosan/Polyvinylpyrrolidone/Dextrin Composite: The Role of Polymeric Adhesive and Particle Size Distribution on Printability of Powders [PDF]
Fahimeh Dini +3 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Composition optimization of mastic in recycled asphalt mixtures based on pavement performance. [PDF]
Li X, Liu Z, Fu K, Zhang K, Chen M.
europepmc +1 more source
Surface-Functionalized Glass Nanoparticles with Algae-Derived Bio-Binder (ADBB) as Reinforcing Agent for Epoxy/ADBB Matrix Nanocomposite [PDF]
Abhijeet Mali +5 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Adsorption Characteristics of Chloride Ions by Calcined Hydrotalcite and Its Influence on the Salt Corrosion Resistance of Asphalt Binder. [PDF]
Sheng J +7 more
europepmc +1 more source

