Results 111 to 120 of about 202,277 (297)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Influence of Mn pellet preparation conditions on nitriding reaction
工程科学学报, 2016 Nitriding reaction of Mn pellets prepared under different conditions was investigated with a self-made air-proofed nitriding system. The effects of Mn particle size, pelletizing pressure and binder content on the nitriding reaction were studied, and the ...
ZHU Xiang-ying, ZHAI Yu-chun
doaj +1 more source
Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate). [PDF]
, 2019 Chronic kidney disease (CKD) is a major cause of morbidity and premature mortality and represents a significant global public health issue. Underlying this burden are the many complications of CKD, including mineral and bone disorders, anemia, and ...
Bino, Avi +2 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Minor groove binders: some recent research in drug development [PDF]
, 2009 The role of the naturally occurring polyamides distamycin and netropsin as antibacterial agents is described. Also, the importance of the modifications to the lipophilic and hydrophobic moieties is discussed.
Khalaf, Abedawn I.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Effect of hyperbranched polyester binders on properties of Fe–Fe3P bonding mixed powders
Fenmo yejin jishuFe–Fe3P adhesive premixed powders were prepared by using hyperbranched polyester as the binders. The microstructure of the powders was observed by scanning electron microscope.
JIANG Huangyong +5 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Development of durable “green” concrete exposed to deicing chemicals via synergistic use of locally available recycled materials and multi-scale modifiers [PDF]
, 2018 From the economic and social perspectives, the use of waste materials would not be attractive until their costs and quality can satisfy the construction requirements.
Cui, Na, Xie, Ning
core