Evaluation of Flavones Binding to Nucleic Acids through Competitive Dialysis
Competitive dialysis is a method in which the selective binding of ligands to nucleic acids can be quantified. This method utilizes the concept of diffusion against a semipermeable membrane to evaluate concentrations of binding.
Jiang, Holly +4 more
core +1 more source
WGM Single-Molecule Validation of pH-Dependent Molecular Energetics at Gold Nanointerfaces: Influence of Buffer Molecules on Glyphosate Ligand Binding. [PDF]
Perera KMK +3 more
europepmc +1 more source
Dirac Semimetallicity Enabled by Stripe Antiferromagnetism in Monolayer FeSe
In monolayer FeSe, stripe antiferromagnetic order selectively breaks mirror symmetry, enabling odd inter‐orbital hybridization between opposite‐parity Fe 3d states. This mechanism stabilizes symmetry‐protected Dirac nodes with nontrivial Wilson‐loop topology and edge states, accompanied by a strong orbital diamagnetic susceptibility as an experimental ...
Darius‐Alexandru Deaconu +5 more
wiley +1 more source
Trypsinogen Pro-Region as a Molecular Scaffold for the Design of Competitive Peptide Inhibitors of Trypsin-Like Proteases. [PDF]
Mariano GA +12 more
europepmc +1 more source
Emergence of a Hexagonal Fe2S2 Single Layer Without a Bulk Counterpart via Phase Transformation
Upon annealing, single‐layer Mackinawite iron sulfide transforms into a previously unknown hexagonal Fe2S2${\rm Fe}_2{\rm S}_2$ phase with β$\beta$‐CuI structure. STM, LEED, and first‐principles calculations identify the structure and show that electronic correlations and magnetic order are important for its stability.
Affan Safeer +10 more
wiley +1 more source
Rapid On-Site Detection of Clarithromycin in Water Using an Evanescent Wave Fluorescence Immunosensor. [PDF]
Zhang W +7 more
europepmc +1 more source
The APTES linker establishes a permanent interfacial dipole, reducing the work function of n‐GaN from 3.55 to 3.29 eV. This strengthens the built‐in electric field, significantly accelerating hole extraction to drive the oxygen evolution reaction (OER). Ultimately, this tailored charge‐separation architecture achieves a remarkable 4.78‐fold enhancement
Jeong‐Kyun Oh +15 more
wiley +1 more source
Targeting PAK1 Within Group I PAKs: Current Challenges and Pharmacological Perspectives. [PDF]
Ion GND +3 more
europepmc +1 more source
Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger +5 more
wiley +1 more source

