Using Molecular Dynamics to Model the Binding Affinities of Nitrogen-Containing Bisphosphonates on Hydroxyapatite Surface [PDF]
arXiv, 2018 Nitrogen-containing bisphosphonates (NBPs) are widely used to treat bone density loss and skeletal disorders. The adsorption, retention, diffusion, and release of (NBPs) in bone minerals are governed by their binding affinities to such minerals. Extensive crystal growth, nuclear magnetic resonance (NMR), and isothermal titration calorimetry (ITC ...
arxiv
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
The vitamin B12-binding systems of isolated intestine of the rat [PDF]
, 1958 A.L. Latner, Laureen Raine
openalex +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
A Binding Energy Calculation on
, 1954 P. G. Wakely
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Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Receptor sites involved in posttranslational transport of apocytochrome c into mitochondria [PDF]
, 1983 Assembly of cytochrome c involves a series of steps: synthesis of apocytochrome c on free ribosomes, specific binding of apocytochrome c to the mitochondrial surface, transfer across the outer membrane, covalent addition of protoheme, refolding of the ...
Hennig, Bernd +2 more
core
Investigations in Serum Copper. I. Nature of Serum Copper and its Relation to the Iron-Binding Protein in Human Serum. [PDF]
, 1947 Carl Holmberg +4 more
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A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini +11 more
wiley +1 more source