Results 261 to 270 of about 8,384,443 (422)

PROTEIN BINDING OF AZO DYES BY TISSUE HOMOGENATES

, 1956
Alexander M. Rutenburg, Arnold M. Seligman   +1 more
openalex   +1 more source

The RNA Binding Protein Quaking Regulates Formation of circRNAs

Cell, 2015
S. Conn, Katherine A. Pillman, J. Toubia, Vanessa M. Conn, M. Salmanidis, Caroline A Phillips, Suraya Roslan, A. Schreiber, P. A. Gregory, G. Goodall   +9 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Structural basis of ubiquitin ligase Nedd4-2 autoinhibition and regulation by calcium and 14-3-3 proteins. [PDF]

Nat Commun
Janosev M, Kosek D, Tekel A, Joshi R, Honzejkova K, Pohl P, Obsil T, Obsilova V.   +7 more
europepmc   +1 more source

THE BINDING OF PENICILLIN IN RELATION TO ITS CYTOTOXIC ACTION [PDF]

, 1954
Harry Eagle
openalex   +1 more source

NetMHCpan-4.0: Improved Peptide–MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data

Journal of Immunology, 2017
V. Jurtz, S. Paul, M. Andreatta, P. Marcatili, Bjoern Peters, M. Nielsen   +5 more
semanticscholar   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

The ALX4 dimer structure provides insight into how disease alleles impact function. [PDF]

Nat Commun
Cain B, Yuan Z, Thoman E, Kovall RA, Gebelein B.   +4 more
europepmc   +1 more source

STUDIES IN SERUM ELECTROLYTES. XV. THE CALCIUM-BINDING PROPERTY OF THE SERUM PROTEINS (MULTIPLE MYELOMA, LYMPHOGRANULOMA VENEREUM AND SARCOIDOSIS) [PDF]

, 1948
Arnold J. Rawson, F. William Sunderman
openalex   +1 more source

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Science, 2017
Yimeng Yin, E. Morgunova, A. Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, P. Das, Teemu Kivioja, Kashyap Dave, F. Zhong, K. Nitta, Minna Taipale, A. Popov, P. Ginno, Silvia Domcke, Jian Yan, D. Schübeler, C. Vinson, J. Taipale   +18 more
semanticscholar   +1 more source