Results 371 to 380 of about 8,384,443 (422)
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To bind or not to bind

Nature Genetics, 2001
Gene expression is regulated by transcription factors binding selectively to particular portions of the genome. To what extent are these protein–DNA interactions influenced by the intrinsic sequence-specific recognition properties at each protein, and to what extent are they affected by other factors, such as chromatin structure or cooperative ...
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Self-Binding Peptides: Folding or Binding?

Journal of Chemical Information and Modeling, 2015
Self-binding peptides (SBPs) represent those short peptide segments within monomeric proteins to fulfill their biological functions by dynamically binding to/unbinding from their target domains in the same monomers. They are frequently found in disordered or unstructured regions of proteins that are now known to be not simply helices, loops, or linkers
Ping He   +5 more
openaire   +2 more sources

Folding for binding or binding for folding?

Trends in Biotechnology, 2003
Abstract A number of proteins are partially unstructured under physiological conditions and assume a well-defined three-dimensional structure only upon binding to another protein or macromolecular complex. Numerous examples have been found, especially among proteins involved in regulatory functions in eukaryotic cells.
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Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.

Annual Review of Biochemistry, 2000
Hemagglutinin (HA) is the receptor-binding and membrane fusion glycoprotein of influenza virus and the target for infectivity-neutralizing antibodies. The structures of three conformations of the ectodomain of the 1968 Hong Kong influenza virus HA have ...
J. Skehel, D. Wiley
semanticscholar   +1 more source

Properties and Bindings

2012
In Chapters 1 and 2, we introduced you to the JavaFX 2.0 platform. You downloaded the JavaFX 2.0 SDK and the JavaFX plugin for Netbeans. You wrote and ran your first JavaFX 2.0 GUI programs. You learned the fundamental building blocks of JavaFX 2.0: the Stage and Scene classes, and the Nodes that go into the Scene. And you have no doubt noticed the use
Weiqi Gao   +4 more
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The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins.

Science, 1988
A 30-amino-acid segment of C/EBP, a newly discovered enhancer binding protein, shares notable sequence similarity with a segment of the cellular Myc transforming protein.
W. Landschulz, P. Johnson, S. McKnight
semanticscholar   +1 more source

Double binds, triadic binds

Semiotica, 2009
Bateson's theory of the double bind has been mistakenly interpreted as pertaining to a simple communication paradox. This article proposes a semiotic reformulation of the double bind as a manipulated breach in a concerted effort to create thirdness. This proposal is guided by an interdisciplinary perspective that investigates the double bind by drawing
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Small GTP-binding proteins.

International Review of Cytology, 1992
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and ...
Y. Takai   +3 more
semanticscholar   +1 more source

Binding of hepatitis C virus to CD81.

Science, 1998
Chronic hepatitis C virus (HCV) infection occurs in about 3 percent of the world's population and is a major cause of liver disease. HCV infection is also associated with cryoglobulinemia, a B lymphocyte proliferative disorder.
P. Pileri   +10 more
semanticscholar   +1 more source

The binding problem

Current Opinion in Neurobiology, 1996
Perceptual representations depend on distributed neural codes for relaying the parts and properties of objects. Some mechanism is needed to 'bind' the information relating to each object and to distinguish it from others. Possible candidates include cells tuned to conjunctions of features, spatial attention, and synchronized firing across separate but ...
openaire   +3 more sources

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