Results 231 to 240 of about 1,526,997 (293)

Chirality and Organization of Adsorbates Modify Surface Phonon Dynamics

Advanced Functional Materials, EarlyView.
Chirality and molecular organization are shown to influence surface phonon dynamics in gold films. Time‐resolved Joule heating measurements reveal that ordered homochiral monolayers increase the Debye temperature and disordered layers reduce it, while ordered racemic controls have no effect.
Meital Ozeri, Eugenia Pyurbeeva, Shira Yochelis, Jonas Fransson, Ronnie Kosloff, Oded Millo, Yossi Paltiel   +6 more
wiley   +1 more source

Crystal structures reveal phosphorylation-dependent disruption of the heat shock protein 70-CHIP interface: A compensatory G132N variant restores binding affinity. [PDF]

Cell Stress Chaperones
Stewart M, Paththamperuma C, McCann C, Cottingim K, Zhang H, DelVecchio R, Peng I, Fennimore E, Nix JC, Saeed MN, George K, Makaroff K, Colie M, Paulakonis E, Almeida MF, Afolayan AJ, Brown NG, Page RC, Schisler JC.   +18 more
europepmc   +1 more source

Efficient Membranes Made of a Nanohybrid of Fluorine‐Doped Carbon Dots Coupled With Metal Organic Framework for High‐Performance Vanadium Redox Flow Battery

Advanced Functional Materials, EarlyView.
A sulfonated poly(ether ether ketone)‐based hybrid membrane is fabricated with fluorine‐doped carbon dot (FCD) and functionalized metal organic framework (MIL−101−NH2). The novel design reduces unwanted ion crossover while maintaining a sufficient proton transport pathway.
Tan Trung Kien Huynh, Nayanthara P. S., Muhammad Fawad Khan, Tong Yang, Zijian Cai, Saveen Senanayake, Yang Yang, Jiaye Ye, Hongxia Wang   +8 more
wiley   +1 more source

Evaluating the FEP+ protocol for predicting binding affinity of congeneric ligands towards various soluble proteins. [PDF]

RSC Med Chem
Sampangin Venkatesh SK, Das A, Lakkaniga NR.   +2 more
europepmc   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Computational study of chalcone-cyanopyrimidine hybrids as LSD1 inhibitors: Assessing the influence of FAD on binding affinity and inhibition. [PDF]

Biochem Biophys Rep
Saifullah MK, Gupta A, Parveen D, Azam F, Alam MM, Akhter M, Parvez S, Maksud N, Azeez N, Shaquiquzzaman M.   +9 more
europepmc   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

CBFβ-SMMHC-driven leukemogenesis requires enhanced RUNX1-DNA binding affinity in mice. [PDF]

J Clin Invest
Zhen T, Cao Y, Dou T, Chen Y, Lopez G, Menezes AC, Wu X, Hammer JA, Cheng J, Garrett L, Anderson S, Kirby M, Wincovitch S, Sisay B, Elkahloun AG, Wu D, Castilla LH, Yang W, Jiang J, Zhao K, Liu PP.   +20 more
europepmc   +1 more source

Multisite λ-Dynamics for Protein-DNA Binding Affinity Prediction. [PDF]

J Chem Theory Comput
Al Masri C, Vilseck JZ, Yu J, Hayes RL.
europepmc   +1 more source

Spatio-temporal learning from molecular dynamics simulations for protein-ligand binding affinity prediction. [PDF]

Bioinformatics
Libouban PY, Parisel C, Song M, Aci-Sèche S, Gómez-Tamayo JC, Tresadern G, Bonnet P.   +6 more
europepmc   +1 more source