Results 51 to 60 of about 7,717,990 (282)
New Commitment Schemes Based on Conjugacy Problems over Rubik’s Groups
Information, 2021 Commitment schemes are important tools in cryptography and used as building blocks in many cryptographic protocols. We propose two commitment schemes by using Rubik’s groups.
Ping Pan +4 more
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
p53 binding to human genome: crowd control navigation in chromatin context
Frontiers in Genetics, 2014 p53 is the most studied human protein because of its role in maintaining genomic stability. Binding to genomic targets is essential for transcription-dependent p53 tumor suppression, but how p53 selects targets remains unclear.
Krassimira eBotcheva
doaj +1 more source
Binding Modes of Ligands Using Enhanced Sampling (BLUES): Rapid Decorrelation of Ligand Binding Modes Using Nonequilibrium Candidate Monte Carlo [PDF]
, 2018 Accurately predicting protein-ligand binding is a major goal in computational chemistry, but even the prediction of ligand binding modes in proteins poses major challenges. Here, we focus on solving the binding mode prediction problem for rigid fragments.
John D., Chodera +7 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Remarks on the Periodic Conformable Sturm–Liouville Problems
Complexity, 2023 The conformable Sturm–Liouville problem (CSLP), −x1−αpxx1−αy′x′=λρx−qxyx, for ...
Wei-Chuan Wang
doaj +1 more source
On the Binding Problem in Artificial Neural Networks
CoRR, 2020 Contemporary neural networks still fall short of human-level generalization, which extends far beyond our direct experiences. In this paper, we argue that the underlying cause for this shortcoming is their inability to dynamically and flexibly bind information that is distributed throughout the network.
Klaus Greff +2 more
openaire +3 more sources
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Wyjaśnienie świadomości a problem scalania [Explanation of Consciousness and Binding Problem] [PDF]
Analiza i Egzystencja, 2012 Consciousness, which failed to explain the earlier philosophers, is now one of thelast scientific mysteries. On the one hand there is no exaggeration to say, that weactually learned to just put the right questions about the mind.
Bogusław Wójcik
doaj
Data of protein-RNA binding sites
Data in Brief, 2017 Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA ...
Wook Lee +3 more
doaj +1 more source