Results 81 to 90 of about 259,971 (305)

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

open access: yesAdvanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang   +16 more
wiley   +1 more source

Binge Eating in the Obese

open access: yesAnnals of Medicine, 1992
This review will first describe problems in the definition of the term binge eating, especially in the absence of purging (vomiting, laxative abuse). We highlight current approaches in the classification of obesity, and then provide an overview of the available literature on differences between obese binge eaters and obese non-binge eaters.
M, de Zwaan, J E, Mitchell
openaire   +2 more sources

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

open access: yesAdvanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang   +15 more
wiley   +1 more source

BING-NEEL SYNDROME: ILLUSTRATIVE CASES AND COMPREHENSIVE REVIEW OF THE LITERATURE

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2017
The Bing-Neel syndrome is a rare neurological complication of Waldenström’s Macroglobulinemia which results from a direct involvement of central nervous system by malignant lymphoplasmacytic cells.
Marzia Varettoni   +5 more
doaj   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

open access: yesAdvanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu   +14 more
wiley   +1 more source

Synergistic Regulation of Deep‐Cycling‐Induced Zn Pulverization and Resting Galvanic Corrosion in Practical Lean Zinc Anodes

open access: yesAdvanced Science, EarlyView.
Benzotriazole (BTA) regulates Zn reduction kinetics and suppresses galvanic corrosion, simultaneously mitigating Zn pulverization during cycling and self‐corrosion during storage, thereby enabling lean Zn anodes with enhanced cycling stability and extended calendar life.
Jing Xu   +7 more
wiley   +1 more source

Bing 9 - Beam Identification by Non-destructive Grading [PDF]

open access: yes, 2007
Bing est un dispositif de contrôle non destructif de la qualité mécanique des bois par méthode vibratoire. Bing est un logiciel de mesure permettant d'obtenir pour tout matériau rigide ses caractéristiques élastiques (module d'élasticité longitudinal ...
Paradis, Sébastien, Brancheriau, Loïc
core  

A Conduction‐Nucleation‐Competition‐Guided 3D Adaptive Gradient Buffer for Dendrite‐Free All‐Solid‐State Lithium Metal Batteries

open access: yesAdvanced Science, EarlyView.
A self‐adaptive gradient SCMN buffer layer is designed based on a conduction‐nucleation competition mechanism. The design dynamically optimizes ion/electron conduction and lithiophilicity, guiding dendrite‐free lithium deposition. Consequently, symmetric cells deliver exceeding 1600h at 1.5 mA cm−2, and the LiCoO2‐based full cells exhibit 98.5 ...
Yaru Shi   +9 more
wiley   +1 more source

Diagnostic Next-generation Sequencing Frequently Fails to Detect MYD88L265P in Waldenström Macroglobulinemia

open access: yesHemaSphere, 2021
Amanda Kofides   +18 more
doaj   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

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