Results 51 to 60 of about 61,598 (309)

MetaBAT 2: an adaptive binning algorithm for robust and efficient genome reconstruction from metagenome assemblies [PDF]

open access: yesPeerJ, 2019
We previously reported on MetaBAT, an automated metagenome binning software tool to reconstruct single genomes from microbial communities for subsequent analyses of uncultivated microbial species.
Dongwan D. Kang   +6 more
doaj   +2 more sources

Compact binning for parallel processing of limited-range functions [PDF]

open access: yes, 2010
Limited-range functions are domain-level optimizations to a class of applications where all input elements contribute to all output elements, based on the distance between two given elements.
Obeid, Nady M.
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

On-line bin-stretching

open access: yesTheoretical Computer Science, 1998
We are given a sequence of items that can be packed into \(m\) unit size bins. In the classical bin packing problem we fix the size of the bins and try to pack the items in the minimum number of such bins. In contrast, in the bin-stretching problem we fix the number of bins and try to pack the items while stretching the size of the bins as least as ...
Yossi Azar, Oded Regev 0001
openaire   +4 more sources

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Binning Metagenomic Contigs Using Contig Embedding and Decomposed Tetranucleotide Frequency

open access: yesBiology
Metagenomic binning is a crucial step in metagenomic research. It can aggregate the genome sequences belonging to the same microbial species into independent bins.
Long Fu, Jiabin Shi, Baohua Huang
doaj   +1 more source

Effect of data binning and frame averaging for micro-CT image acquisition on the morphometric outcome of bone repair assessment

open access: yesScientific Reports, 2022
Despite the current advances in micro-CT analysis, the influence of some image acquisition parameters on the morphometric assessment outcome have not been fully elucidated.
Milena Suemi Irie   +4 more
doaj   +1 more source

Employment Trajectories of Patients With Systemic Lupus Erythematosus and Factors Driving Transitions Between States

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo   +4 more
wiley   +1 more source

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