Results 1 to 10 of about 118,651 (117)

How much metagenome data is needed for protein structure prediction: The advantages of targeted approach from the ecological and evolutionary perspectives

open access: yesiMeta, 2022
It has been proven that three‐dimensional protein structures could be modeled by supplementing homologous sequences with metagenome sequences. Even though a large volume of metagenome data is utilized for such purposes, a significant proportion of ...
Pengshuo Yang, Kang Ning
exaly   +2 more sources

TOFU-MAaPO: fast, scalable and reproducible analysis of large metagenome sequence data from the Sequence Read Archive [PDF]

open access: yesNature Communications
Metagenomic shotgun sequencing data from over 600,000 metagenomes are publicly available in repositories such as NCBI’s Sequence Read Archive (SRA).
Eike Matthias Wacker   +3 more
doaj   +2 more sources

High-Resolution Metagenomics of Human Gut Microbiota Generated by Nanopore and Illumina Hybrid Metagenome Assembly

open access: yesFrontiers in Microbiology, 2022
Metagenome assembly is a core yet methodologically challenging step for taxonomic classification and functional annotation of a microbiome. This study aims to generate the high-resolution human gut metagenome using both Illumina and Nanopore platforms ...
Lianwei Ye, Ning Dong, Wenguang Xiong
exaly   +3 more sources

Phage therapy for Clostridioides difficile infection

open access: yesFrontiers in Immunology, 2022
Clostridioides difficile is endemic in the intestinal tract of healthy people. However, it is responsible for many healthcare-associated infections, such as nosocomial diarrhea following antibiotic treatment.
Kosuke Fujimoto   +3 more
doaj   +1 more source

Vaginal Microbiome Metagenome Inference Accuracy: Differential Measurement Error according to Community Composition

open access: yesmSystems, 2023
Several studies have compared metagenome inference performance in different human body sites; however, none specifically reported on the vaginal microbiome.
Kayla A. Carter   +8 more
doaj   +1 more source

Integrating pan-genome with metagenome for microbial community profiling

open access: yesComputational and Structural Biotechnology Journal, 2021
Advances in sequencing technology have led to the increased availability of genomes and metagenomes, which has greatly facilitated microbial pan-genome and metagenome analysis in the community.
Chaofang Zhong   +3 more
doaj   +1 more source

Persistent memory as an effective alternative to random access memory in metagenome assembly

open access: yesBMC Bioinformatics, 2022
Background The assembly of metagenomes decomposes members of complex microbe communities and allows the characterization of these genomes without laborious cultivation or single-cell metagenomics. Metagenome assembly is a process that is memory intensive
Jingchao Sun   +5 more
doaj   +1 more source

NeSSM: a Next-generation Sequencing Simulator for Metagenomics. [PDF]

open access: yesPLoS ONE, 2013
BackgroundMetagenomics can reveal the vast majority of microbes that have been missed by traditional cultivation-based methods. Due to its extremely wide range of application areas, fast metagenome sequencing simulation systems with high fidelity are in ...
Ben Jia   +5 more
doaj   +1 more source

Terabase-Scale Coassembly of a Tropical Soil Microbiome

open access: yesMicrobiology Spectrum, 2023
Petabases of environmental metagenomic data are publicly available, presenting an opportunity to characterize complex environments and discover novel lineages of life.
Robert Riley   +16 more
doaj   +1 more source

TAMA: improved metagenomic sequence classification through meta-analysis

open access: yesBMC Bioinformatics, 2020
Background Microorganisms are important occupants of many different environments. Identifying the composition of microbes and estimating their abundance promote understanding of interactions of microbes in environmental samples.
Mikang Sim   +4 more
doaj   +1 more source

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