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Metagenomics and antibiotics [PDF]
Clinical Microbiology and Infection, 2012 Most of the bacterial species that form part of the biosphere have never been cultivated. In this situation, a comprehensive study of bacterial communities requires the utilization of non-culture-based methods, which have been named metagenomics.
Garmendia, L. +3 more
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DNA Research, 2022 Abstract Various microorganisms exist in environments, and each of which has an optimal growth temperature (OGT). The relationship between genomic information and OGT of each species has long been studied, and one such study revealed that OGT of prokaryotes can be accurately predicted based on the fraction of seven ...
Masaomi Kurokawa +6 more
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Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
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Microbiome, 2020 Background Despite recent decreases in the cost of sequencing, shotgun metagenome sequencing remains more expensive compared with 16S rRNA amplicon sequencing.
Shan Sun +2 more
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MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities [PDF]
PeerJ, 2015 Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions.
Dongwan D. Kang +3 more
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Nature Reviews Genetics, 2019 Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing how physicians diagnose and treat infectious disease, with applications spanning a wide range of ...
Charles Y. Chiu, Steven A. Miller
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Data in Brief, 2019 Transcriptome analysis using next generation sequencing (NGS) technology provides the capability to understand global changes in gene expression throughout a range of tissue samples. The nematode Caenorhabditis elegans (C.
Scott T. Schumacker +3 more
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PLoS ONE, 2020 Determination of metagenome composition is still one of the most interesting problems of bioinformatics. It involves a wide range of mathematical methods, from probabilistic models of combinatorics to cluster analysis and pattern recognition techniques ...
Valery Kirzhner +2 more
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PLoS Computational Biology, 2010 Metagenomics is a discipline that enables the genomic study of uncultured microorganisms. Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of the microbial world.
Bourne, Philip E. +3 more
openaire +6 more sources
Genomics Data, 2015 Bacterial diversity and archaeal diversity in metagenome of the Lonar soda lake sediment were assessed by bacterial tag-encoded FLX amplicon pyrosequencing (bTEFAP).
Pravin Dudhagara +4 more
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