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The Chernoff Modification of the Fisher Exact Test for the Difference of Two Binomial Probabilities [PDF]

open access: yes
To test the difference of two binomial probabilities, we will apply the Fisher exact test modified by Chernoff (2002), which will be called CMF test. The key idea is to use the P-value of Fisher exact test as a test statistic and this makes it possible ...
Takahashi, Hajime, Uematsu, Kazuki
core  

On the time value of ruin in the discrete time risk model [PDF]

open access: yes, 2002
Using an approach similar to that of Gerber and Shiu (1998), a recursive formula is given for the expected discounted penalty due at ruin, in the discrete time risk model. With it the joint distribution of three random variables is obtained; time to ruin,
Garrido, José, Li, Shuanming
core   +1 more source

Differential expression analysis for sequence count data [PDF]

open access: yes, 2010
*Motivation:* High-throughput nucleotide sequencing provides quantitative readouts in assays for RNA expression (RNA-Seq), protein-DNA binding (ChIP-Seq) or cell counting (barcode sequencing).
Simon Anders   +2 more
core   +1 more source

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

open access: yesAdvanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li   +6 more
wiley   +1 more source

Approximation of binomial probability function for a normal probability function

open access: yes, 2016
Educação Superior::Ciências Exatas e da Terra::MatemáticaThe digital animation presents the approximation of the function of the binomial probability for a function of normal probability, also known as Gaussian distribution.
Rojo, Isabel Martín   +3 more
core   +2 more sources

Option Implied Risk-Neutral Distributions and Implied Binomial Trees: A Literature Review [PDF]

open access: yes
In this selective literature review, we start by observing that in efficient markets, there is information incorporated in option prices that might help us to design option pricing models.
Jackwerth, Jens Carsten
core  

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

open access: yesAdvanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang   +12 more
wiley   +1 more source

Numerics of Implied Binomial Trees [PDF]

open access: yes
Market option prices in last 20 years conrmed deviations from the Black and Scholes (BS) models assumptions, especially on the BS implied volatility.
Wolfgang Härdle, Alena Mysickova
core  

Confidence Regions for the Multinomial Parameter With Small Sample Size [PDF]

open access: yes, 2009
Consider the observation of n iid realizations of an experiment with d >= 2 possible outcomes, which corresponds to a single observation of a multinomial distribution M_d(n; p) where p is an unknown discrete distribution on \{1,...,d\}.
Concordet, Didier   +3 more
core   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

open access: yesAdvanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su   +7 more
wiley   +1 more source

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