Results 81 to 90 of about 269,869 (292)

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

A BINOMIAL DIOPHANTINE EQUATION [PDF]

open access: yesThe Quarterly Journal of Mathematics, 1996
A complete set of solutions in integers \(n\geq 2\) and \(m\geq 4\) is given for the binomial diophantine equation \[ {n\choose 2}={m\choose 4}.\tag{1} \] Setting \(u=2n-1\), \(v=2m-3\), equation (1) takes the form \[ 48u^2=v^4- 10v^2+57,\tag{2} \] which shows that (1) represents an elliptic curve.
openaire   +3 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Semantical and Grammatical Peculiarities of Binomial Expressions in English

open access: yes, 2011
Binomial expressions are a sequence of two or more words or phrases, which consist of elements belonging to the same category. They may be connected by a coordinating conjunction or a preposition.
Котнюк Л. Г.
core  

On the time value of ruin in the discrete time risk model [PDF]

open access: yes, 2002
Using an approach similar to that of Gerber and Shiu (1998), a recursive formula is given for the expected discounted penalty due at ruin, in the discrete time risk model. With it the joint distribution of three random variables is obtained; time to ruin,
Garrido, José, Li, Shuanming
core  

Hybrid binomial Langevin-multiple mapping conditioning modeling of a reacting mixing layer [PDF]

open access: yes, 2009
A novel, stochastic, hybrid binomial Langevin-multiple mapping conditioning (MMC) model—that utilizes the strengths of each component—has been developed for inhomogeneous flows.
Lindstedt, R. Peter   +3 more
core   +1 more source

Novel Binomial Series without Binomial Coefficients

open access: yes, 2023
Nowadays, the growing complexity of mathematical and computational modelling demands the simplicity of mathematical equations for solving today’s scientific problems and challenges. For this purpose, a novel binomial series (new binomial theorem) without
Chinnaraji Annamalai
core   +1 more source

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Approximation of binomial probability function for a normal probability function

open access: yes, 2011
Notions of statistics and probabilityThe digital animation presents the approximation of the function of the binomial probability for a function of normal probability, also known as Gaussian distribution.
Rojo, Isabel Martín   +3 more
core   +1 more source

Forest management decision making based on a real options approach: An application to a case in northeastern Argentina

open access: yesMetsanduslikud Uurimused, 2017
The Net Present Value (NPV) approach is widely applied to assess forest investments, but this method has serious shortcomings, which we propose to overcome by switching to the assessment through the Real Options Approach (ROA).
Broz Diego   +4 more
doaj   +1 more source

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