Results 41 to 50 of about 99,718 (252)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Linguistic Rigidity of Gender Binomials

Научный диалог
This article examines the linguistic rigidity of the components of gender binomials, particularly the pairs “man and woman” and “husband and wife.” The study draws on texts from the media, specifically a newspaper subcorpus of the Russian National Corpus.
M. V. Milovanova, E. V. Terentyeva
doaj   +1 more source

Les binômes et multinômes dans une sélection de sermons anglo-normands et leur traduction en moyen-anglais : le cas du Mirur de Robert de Gretham [PDF]

Studii de Lingvistica
This article aims to analyse binomial and multinomial constructions in a selection of 13th-century Anglo-Norman sermons, Robert of Gretham’s cycle Mirur (the first twelve sermons, from Advent to Sexagesima). The study will follow the typology proposed by
Teodora Martin Sava
doaj   +1 more source

Constructing Arbitrage-free Binomial Models [PDF]

, 2004
Wöster C. Constructing Arbitrage-free Binomial Models. Discussion paper / Fakultät für Wirtschaftswissenschaften, Universität Bielefeld. Bielefeld: Universität Bielefeld; 2004.In the past decades several versions of the binomial model for option pricing,
Wöster, Christoph
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

On skewed, leptokurtic returns and pentanomial lattice option valuation via minimal entropy martingale measure

Cogent Economics & Finance, 2017
This article develops, a lattice-based approach for pricing contingent claims when parameters governing the logs of the underlying asset dynamics are modelled by generalized hyperbolic distribution and normal inverse Gaussian distribution.
Ivivi J. Mwaniki
doaj   +1 more source

LIQUIDITY IN A BINOMIAL MARKET

Mathematical Finance, 2010
We study the binomial version of the illiquid market model introduced by Çetin, Jarrow, and Protter for continuous time and develop efficient numerical methods for its analysis. In particular, we characterize the liquidity premium that results from the model.
Gökay, Selim, Soner, Halil Mete
openaire   +4 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The validation of a beta-binomial model for overdispersed binomial data [PDF]

Communications in Statistics - Simulation and Computation, 2016
The beta-binomial model has been widely used as an analytically tractable alternative that captures the overdispersion of an intra-correlated, binomial random variable, X. However, the model validation for X has been rarely investigated. As a beta-binomial mass function takes on a few different shapes, the model validation is examined for each of the ...
Jongphil Kim, Ji-Hyun Lee
openaire   +2 more sources

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source