Results 111 to 120 of about 160,421 (323)

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan   +5 more
wiley   +1 more source

Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia   +24 more
wiley   +1 more source

Comparative Safety Profiles of Ocrelizumab and Rituximab in Multiple Sclerosis Treatment Using Real‐World Evidence

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to compare the long‐term safety profiles of ocrelizumab and rituximab in persons with multiple sclerosis (MS). Methods Using retrospective data from the University of California (UC) Health System, we simulated a target clinical trial. The primary cohort from UC San Francisco (UCSF) and a validation cohort from
Gabriel Cerono   +3 more
wiley   +1 more source

Identifying Predictive Biomarkers of Response in Patients With Rheumatoid Arthritis Treated With Adalimumab Using Machine Learning Analysis of Whole‐Blood Transcriptomics Data

open access: yesArthritis &Rheumatology, EarlyView.
Objective Tumornecrosis factor inhibitors (TNFi) have significantly improved rheumatoid arthritis (RA) management, yet variability in patient response remains a substantial challenge, with approximately 40% of patients discontinuing TNFi due to nonresponse or adverse effects.
Chuan Fu Yap   +12 more
wiley   +1 more source

Triple Symmetric Sums of Circular Binomial Products

open access: yesMathematics
By employing the generating function approach, 16 triple sums for circular binomial products of binomial coefficients are examined. Recurrence relations and generating functions are explicitly determined.
Marta Na Chen, Wenchang Chu
doaj   +1 more source

Series associated with harmonic numbers, Fibonacci numbers and central binomial coefficients $binom{2n}{n}$ [PDF]

open access: yesNotes on Number Theory and Discrete Mathematics
We find various series that involve the central binomial coefficients $binom{2n}{n}$, harmonic numbers and Fibonacci numbers. Contrary to the traditional hypergeometric function _pF_q approach, our method utilizes a straightforward transformation to ...
Segun Olofin Akerele   +1 more
doaj   +1 more source

On sums of binomial coefficients and their applications

open access: yesDiscrete Mathematics, 2008
In this paper we study recurrences concerning the combinatorial sum $[n,r]_m=\sum_{k\equiv r (mod m)}\binom {n}{k}$ and the alternate sum $\sum_{k\equiv r (mod m)}(-1)^{(k-r)/m}\binom{n}{k}$, where m>0, $n\ge 0$ and r are integers. For example, we show that if $n\ge m-1$ then $$\sum_{i=0}^{\lfloor(m-1)/2\rfloor}(-1)^i\binom{m-1-i}i [n-2i,r-i]_m=2^{n-
openaire   +3 more sources

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