Results 111 to 120 of about 4,871,983 (290)

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang   +6 more
wiley   +1 more source

Estimating survival rates in ecological studies with small unbalanced sample sizes: an alternative Bayesian point estimator [PDF]

open access: yesComputational Ecology and Software, 2011
Increasingly, the survival rates in experimental ecology are presented using odds ratios or log response ratios, but the use of ratio metrics has a problem when all the individuals have either died or survived in only one replicate.
Christian Damgaard, Adeline Fayolle
doaj  

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

Application of binomial distribution-based statistical process control method in blood quality control

open access: yesZhongguo shuxue zazhi
Objective This study endeavors to introduce the statistical process control (SPC) method to analyze the quality control index concerning red blood cells in additive solution with leukocytes reduced, with the aspiration to advance the effective ...
Xingchen LIU   +7 more
doaj   +1 more source

Generalized distributions of order k associated with success runs in Bernoulli trials

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2003
In a sequence of independent Bernoulli trials, by counting multidimensional lattice paths in order to compute the probability of a first-passage event, we derive and study a generalized negative binomial distribution of order k, type I, which extends to ...
Gregory A. Tripsiannis   +2 more
doaj   +1 more source

Curvature‐Directed Elongation and Chiral Tilting Drive Asymmetric Tissue Patterning

open access: yesAdvanced Science, EarlyView.
Curvature and cell handedness together break tissue symmetry. On convex and concave surfaces, cells elongate along opposite geometric axes and tilt in a consistent chirality‐driven direction, yielding opposite alignment patterns from the same cells. Reversing intrinsic cell chirality reverses both.
Liyao Xu   +6 more
wiley   +1 more source

Estudio de homogeneidad de la dispersión en diseño a una vía de clasificación para datos de proporciones y conteos

open access: yesRevista Colombiana de Estadística, 2009
En el modelamiento de datos donde se evidencia la presencia de sobredispersión, usualmente se asume que para todos los efectos de tratamiento el parámetro de sobredispersión es común.
MARIO ALFONSO MORALES   +1 more
doaj  

Estimation of the Binominal Distribution Parameters Using the Method of Moments and Its Asymptotic Properties [PDF]

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2016
The problem of estimating the parameters m and p of the binomial distribution for a sample having the fixed volume n with the help of the method of moments is considered in this paper.
A.N. Safiullina
doaj  

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

open access: yesAdvanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng   +16 more
wiley   +1 more source

PITTING THE BINOMIAL DISTRIBUTION TO THE SEX DISTRIBUTION OF FAMILY CHILDREN

open access: yesIranian Journal of Public Health, 1975
در اين مطالعه 2833 خانوار (1402 خانوار مسلمان و 1431 خانوار ارامنه) را که مجموعاً 11324 فرزند (بطور متوسط 4 فرزند براي هر خانوار) داشته اند از طرح مجيديه " طرح بررسي بعد خانوار" استخراج مورد استفاده قرار گرفته است. خانوارهاي مورد مطالعه کليه خانواده هايي
Firooz Azordcgan
doaj  

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