Results 91 to 100 of about 4,871,983 (290)

DyProL: Dynamic Ensemble Representation Learning for Protein–Nucleic Acid Binding Site Prediction

Advanced Science, EarlyView.
Protein function is represented as a dynamic conformational ensemble rather than a single static structure. A multi‐conformation geometric attention framework aligns, clusters, and learns representative states to capture residue‐ and ensemble‐level signals. Integrating structural dynamics improves interpretable protein‐NA binding prediction and reveals
Pengpai Li, Yiman Liu, Liya Liang, Rongming Liu   +3 more
wiley   +1 more source

A generalization of the negative binomial distribution

Journal of Biostatistics and Epidemiology, 2017
Background & Aim: Consider a sequence of independent Bernoulli trials with p denoting the probability of success at each trial. With this definition, the probability that the nth success proceed by r failures follows the negative binomial distribution ...
Maryam Nazemipour, Mahmood Mahmoudi
doaj  

Bounds for median and 50 percetage point of binomial and negative binomial distribution

Binomial, Negative Binomial Distribution Function, Operating Characteristic Function, 50 Percentage Point, Median,
Rainer Göb
core   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

A type of Binomial mixture distribution

, 2014
A brief introduction to a type of binomial mixture distribution, generated from a beta exponential distribution.
Ruth Ogal (554154)
core   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

Advanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao, Ting‐Yu Han, Yan‐Li Cheng, Yi‐Dan Zhang, Yu‐Wei Zhang, JinJian Guo, ShaoJun Zhang, WenZe Huang, Jing Zhang, Pei‐Yu Liao, Ying Xin, ChuanChen Chu, Qing‐Yuan Sun, ZhiZhen Liu, Xiang‐Hong Ou, Jun Xie   +15 more
wiley   +1 more source

Applying Negative Binomial Distribution in Diagnostic Classification Models for Analyzing Count Data. [PDF]

Appl Psychol Meas, 2023
Liu R, Heo I, Liu H, Shi D, Jiang Z.
europepmc   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

Advanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan, Erdi Zhang, Yuwen Ma, Zirui Meng, Sisi Li, Yimeng Ren, Xiaohe Tian, Yangyi He, Giuseppe Battaglia, Dong Zhou, Yun Liao, Binwu Ying, Jinmei Li, Minjin Wang   +13 more
wiley   +1 more source

One Parameter Polynomial Exponential Distribution with Binomial Mixture

Revstat Statistical Journal
A further generalized version of one parameter polynomial exponential distribution with binomial probability mass as a mixture called a Binomial Mixture One Parameter Polynomial Exponential Distribution (BMOPPE) is proposed in the article.
Molay Kumar Ruidas, Indrani Mukherjee, Mriganka Mouli Choudhury, Sudhansu S. Maiti , Sumanta Adhya   +4 more
doaj   +1 more source

Logistic Regression Model for a Bivariate Binomial Distribution with Applications in Baseball Data Analysis. [PDF]

Entropy (Basel), 2022
Han Y, Kim J, Ng HKT, Kim SW.
europepmc   +1 more source