Results 31 to 40 of about 1,115,015 (264)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Solvent-free processing of lignin into robust room temperature phosphorescent materials

Nature Communications
Producing room temperature phosphorescent (RTP) materials from biomass resources using a solvent free method is essential but hard to achieve. Here, we discovered that lignin dissolved well in the liquid monomer, 2-hydroxyethyl acrylate (HEA), due to ...
Min Wang, Wei-Ming Yin, Yingxiang Zhai, Jingyi Zhou, Shouxin Liu, Jian Li, Shujun Li, Tony D. James, Zhijun Chen   +8 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Photoactivated room temperature phosphorescence from lignin

Nature Communications
Sustainable photoactivated room temperature phosphorescent materials exhibit great potential but are difficult to obtain. Here, we develop photoactivated room temperature phosphorescent materials by covalently attaching lignin to polylactic acid, where ...
Jingyi Zhou, Bing Tian, Yingxiang Zhai, Min Wang, Shouxin Liu, Jian Li, Shujun Li, Tony D. James, Zhijun Chen   +8 more
doaj   +1 more source

Mechanically Strong, Low Thermal Conductivity and Improved Thermal Stability Polyvinyl Alcohol–Graphene–Nanocellulose Aerogel

Gels, 2021
Porous aerogel materials have advantages of a low density, low thermal conductivity and high porosity, and they have broad application prospects in heat insulation and building energy conservation.
Xiuya Wang, Pengbo Xie, Ke Wan, Yuanyuan Miao, Zhenbo Liu, Xiaojun Li, Chenxi Wang   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Up-recycling of waste wood into value-added room temperature phosphorescent materials

Nature Communications
Up-recycling waste wood as a source for producing materials is crucial for sustainability. Here, we discovered that in situ thermal curing of melamine-formaldehyde resin (MF) with natural wood enhanced its room temperature phosphorescence (RTP ...
Wei-Ming Yin, Ben Dang, Sitong Guo, Min Sun, Yuan-Ru Guo, Shouxin Liu, Shujun Li, Jian Li, Tony D. James, Zhijun Chen   +9 more
doaj   +1 more source

Enhancing compatibility and biodegradability of polylactic acid/biomass composites through torrefaction of forest residue

Journal of Bioresources and Bioproducts
This study investigated the effects of torrefaction on forest residue (FR) and its subsequent application as a bulk-loading filler in polylactic acid (PLA) composites.
June-Ho Choi, Myeong Rok Ahn, Chae-Hwi Yoon, Yeon-Su Lim, Jong Ryeol Kim, Hyolin Seong, Chan-Duck Jung, Sang-Mook You, Jonghwa Kim, Younghoon Kim, Hyun Gil Cha, Jae-Won Lee, Hoyong Kim   +12 more
doaj   +1 more source

Ultralight, Mechanically Enhanced, and Thermally Improved Graphene-Cellulose-Polyethyleneimine Aerogels for the Adsorption of Anionic and Cationic Dyes

Nanomaterials, 2022
Graphene-cellulose-polyethyleneimine aerogels (GA-MCC-PEI) were prepared using a simple, environmentally friendly method to remove anionic and cationic dyes in water.
Xiuya Wang, Pengbo Xie, Lan He, Yuwei Liang, Liang Zhang, Yuanyuan Miao, Zhenbo Liu   +6 more
doaj   +1 more source