Results 51 to 60 of about 23,834,518 (309)

To be, or not to be biodegradable… that is the question for the bio‐based plastics

Microbial Biotechnology, 2016
Summary Global warming, market and production capacity are being the key drivers for selecting the main players for the next decades in the market of bio‐based plastics. The drop‐in bio‐based polymers such as the bio‐based polyethylene terephtalate (PET) or polyethylene (PE), chemically identical to their petrochemical counterparts ...
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Constructing an Adenine Base Editor in Escherichia coli for Fine-Tuning the 1,4-Butanediamine Biosynthetic Pathway

Microorganisms
Adenine base editors (ABEs) can be used to fine-tune metabolic flux by editing gene promoters. However, their targeting scope is constrained by the PAM requirement of Cas9, making it difficult to target promoter regions where NGG motifs are rare.
Yanling Sun, Di Ma, Kexin Zhao, Shihao Liu, Weichao Chen, Bixin He, Wei Huang, Fuping Lu, Ming Li   +8 more
doaj   +1 more source

Activity Prediction of Schiff Base Compounds using Improved QSAR Models of Cinnamaldehyde Analogues and Derivatives

BioResources, 2015
In past work, QSAR (quantitative structure-activity relationship) models of cinnamaldehyde analogues and derivatives (CADs) have been used to predict the activities of new chemicals based on their mass concentrations, but these approaches are not without
Hui Wang, Haijian Yuan, Shujun Li, Zhuo Li, Mingyue Jiang, Jiafa Tang   +5 more
doaj   +1 more source

Development and Application of Bio-Based Polymers

This reprint highlights pioneering research on bio-based polymers, introducing novel strategies for creating eco-friendly materials derived from renewable sources. The articles cover the complete lifecycle of bio-based polymers, from their production and

core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Correction to: Enhancement of the catalytic activity of Isopentenyl diphosphate isomerase (IDI) from Saccharomyces cerevisiae through random and site-directed mutagenesis

Microbial Cell Factories, 2020
The authors of this article [1] wish to draw the readers’ attention to their closely related paper, published in RSC Advances [2] which should have been cited in this article.
Hailin Chen, Meijie Li, Changqing Liu, Haibo Zhang, Mo Xian, Huizhou Liu   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

High-strength, multi-mode processable bamboo molecular bioplastic enabled by solvent-shaping regulation

Nature Communications
The global reliance on petrochemical plastics has led to severe environmental crises, necessitating sustainable alternatives that combine high performance with circularity. While bioplastics derived from biomass show promise, their widespread adoption is
Hongying Tang, Zhihan Tong, Rui Zhang, Xiaona Li, Suqing Zeng, Dawei Zhao, Haipeng Yu   +6 more
doaj   +1 more source