Results 71 to 80 of about 17,288,534 (269)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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Nature CommunicationsHydroplastics with water-plasticizing effects and programmability are highly desired yet challenges arise from assembling renewable cellulose into hydroplastics with reversible adhesion and enhanced mechanical performance through water-enhancement ...
Guozhuo Chen +6 more
doaj +1 more source
An in vitro synthetic biosystem based on acetate for production of phloroglucinol
BMC Biotechnology, 2017 Background Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established.
Rubing Zhang +5 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Oxygen-Deficient TiO2 Aerogel for Enhanced Photocatalytic Performance
GelsLow charge-separation efficiency is a major factor limiting the photoelectric conversion performance of TiO2. In this work, oxygen-vacancy-rich porous TiO2 gel photocatalyst was successfully fabricated.
Haochen Jiao +6 more
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Materials & Design, 2019 Inspired by the hierarchical micro/nanoscale structure and interfacial interactions of natural nacre, a variety of bioinspired layered materials were designed and prepared.
Muzhi Li +8 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Bio-Medical Library Bulletin, No. 78 (1983-04)
, 1983 Bio-Medical Library. (1983). Bio-Medical Library Bulletin, No. 78 (1983-04).
Bio-Medical Library
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source