Results 81 to 90 of about 1,195,600 (311)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Hop Compost Tea Trial [PDF]

, 2015
As the acreage of hops continues to rapidly expand in the northeast, there is a great need for production knowledge specific to our region. Downy mildew has been identified as the primary pathogen plaguing our hop yards. This disease causes reduced yield,
Calderwood, Lily, Cubins, Julija, Cummings, Erica, Darby, Heather, Gupta, Abha, Post, Julian, Ziegler, Sara   +6 more
core   +1 more source

The EU bio-based industry: Results from a Survey [PDF]

, 2016
Providing regular analysis and data is fundamental for policy makers and stakeholders to monitor the development of an economic sector and make the necessary decisions to maximize the benefits it generates, be them of economic, social or environmental ...
BAUEN Ausilio, BIGGS Clifford, GOMEZ BARBERO Manuel, NATRASS Lucy, PARISI CLAUDIA, RODRIGUEZ CEREZO Emilio   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

An in vitro synthetic biosystem based on acetate for production of phloroglucinol

BMC Biotechnology, 2017
Background Phloroglucinol is an important chemical, and the biosynthesis processes which can convert glucose to phloroglucinol have been established.
Rubing Zhang, Wei Liu, Yujin Cao, Xin Xu, Mo Xian, Huizhou Liu   +5 more
doaj   +1 more source

Fully bio-based aromatic–aliphatic copolyesters: poly(butylene furandicarboxylate-co-succinate)s obtained by ring opening polymerization [PDF]

, 2017
Poly(butylene 2,5-furandicarboxylate-co-succinate) copolyesters (coPBFxSy) have been synthesized by ring opening polymerization (ROP). Cyclic butylene 2,5-furandicarboxylate and butylene succinate oligomer mixtures, to be used as monomers for ROP, were
Batista Ciulik, Claudio, Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon, Morales Huerta, Juan Carlos, Muñoz Guerra, Sebastián   +3 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Gradient Structure Construction of High Thermal Conductivity Polyurethane/Boron Nitride Composite Fiber Membrane for Thermal Management

Molecules
Accompanied by the rapid progress of the digital era and the continuous innovation of material science and technology, wearable electronic devices are widely used in various industries due to their excellent portability and flexibility.
Zhengyang Miao, Jingwei Li, Yidan Liu, Fang Jiang   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Room temperature phosphorescent wood hydrogel

Nature Communications
Room temperature phosphorescent (RTP) hydrogels exhibit great potential but show poor mechanical performance (Tensile strengthen
Ruixia Liu, Hongda Guo, Shouxin Liu, Jian Li, Shujun Li, Tony D. James, Zhijun Chen   +6 more
doaj   +1 more source