Results 71 to 80 of about 244,930 (304)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Hydrothermal Liquefaction of Rice Straw Using Methanol as Co-Solvent

, 2020
Hydrothermal liquefaction (HTL) is a promising thermochemical process to treat wet feedstocks and convert them to chemicals and fuels. In this study, the effects of final temperature (300, 325, and 350 °C), reaction time (30 and 60 min), rice-straw ...
Attada Yerrayya, S. Shreyas, Ravikrishnan Vinu, S. R. Chakravarthy, A. K. Shree Vishnu   +4 more
core   +1 more source

Direct conversion of hemicellulose in biomass to functional diformylxylose with a recyclable organic co-solvent

Industrial Crops and Products
A viable biorefinery platform requires the effective conversion of biomass’s components (cellulose, lignin, and hemicellulose) into high-value chemicals, biofuels, and building blocks for functional materials.
Xiaodi Wang, Ruijie Wu, Yongchao Zhang, Yingjuan Fu, Menghua Qin, Chunlin Xu   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A novel switchable-hydrophilicity, natural deep eutectic solvent (NaDES)-based system for bio-safe biorefinery

, 2018
A switchable-hydrophilicity solvent system, consisting of a fatty acid-based natural deep eutectic solvent (NaDES), complemented by a bio-friendly dilute amine solution, has been introduced.
Sed, Giorgia, Cicci, Agnese, Philip G. Jessop, Agnese Cicci, Bravi, Marco, Giorgia Sed, Jessop, Philip G., Marco Bravi   +7 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Synthesis of amides from acid chlorides and amines in the bio-based solvent Cyrene™ [PDF]

, 2019
Cyrene™ as a bio-alternative dipolar aprotic solvent: a waste minimizing and molar efficient protocol for the synthesis of amides from acid chlorides and primary amines in the bio-available solvent Cyrene™ is disclosed.
Nyamini, Simbarashe, Bousfield, Thomas, Pearce, Katharine, Camp, Jason, Pearce, Katharine P. R., Bousfield, Thomas W., Nyamini, Simbarashe B., Angelis-Dimakis, Athanasios   +7 more
core   +1 more source

Green fabrication of poly(lactic acid) fibers via microfluidic wet spinning

Cleaner Materials
Green processing of porous poly(lactic acid) (PLA) fibers remains challenging primarily due to the lack of ideal bio-based solvents for PLA spinning. In our previous study, green microfluidic wet spinning (MWS) of PLA fibers was achieved by using a PLA ...
Wuchao Wang, Asli Gizem Cinar, Lucyna Hämmerle, René M. Rossi, Kongchang Wei   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

TS-BTPhen as a Promising Hydrophilic Complexing Agent for Selective Am(III) Separation by Solvent Extraction

, 2015
The novel hydrophilic back-extraction agent TS-BTPhen (3,3’,3’’,3’’’-[3-(1,10-phenanthroline-2,9-diyl)-1,2,4-triazine-5,5,6,6-tetrayl]tetrabenzenesulfonic acid) was tested for its selectivity towards Am(III) over Cm(III) and Eu(III) with a TODGA (N,N,N ...
Kaufholz, P., Modolo, G., Lewis, F. W., Wilden, A., Lewis, Frank, Smith, Andrew W., Sadowski, F., Modolo, Giuseppe, Lewis, Frank W., Harwood, Laurence, Kaufholz, Peter, Wilden, Andreas, Smith, A. W., Harwood, L. M., Harwood, Laurence M., Sadowski, Fabian   +15 more
core   +1 more source