Results 51 to 60 of about 87,933 (261)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Journal of Fluid Science and Technology, 2011 Numerical study on the mass transfer in a two-dimensional channel with the transversely oscillating wall was carried out as the basic study to understand the mass transfer of the infused drug into the blood flow.
Masahide NAKAMURA +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Unsteady Propulsion by an Intermittent Swimming Gait
, 2017 Inviscid computational results are presented on a self-propelled swimmer modeled as a virtual body combined with a two-dimensional hydrofoil pitching intermittently about its leading edge.
Akoz, Emre, Moored, Keith W.
core +1 more source
Enhancement of synthetic jets by means of an integrated valve-less pump Part II. Numerical and experimental studies [PDF]
, 2005 The paper studies the performance of the new fluid jet actuator based on the novel principle of the generation of fluid jet, which has been presented in [Z. Travnicek, A.I. Fedorchenko, A.-B.
Tesar, V., Travniceka, Z., Wang, A.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Finite element analysis of non-isothermal multiphase porous media in dynamics [PDF]
, 2015 This work presents a mathematical and a numerical model for the analysis of the thermo-hydro-mechanical (THM) behavior of multiphase deformable porous materials in dynamics.
Sanavia, Lorenzo, Toan Duc, Cao
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Effect of the Blood Vessel Viscoelasticity on Periodic Blood Pressure Wave Propagation
Journal of Fluid Science and Technology, 2009 Clinical arterial stiffness indexes such as PWV (pulse wave velocity) or PP (pulse pressure), which are obtained by analyzing blood pressure pulse waveforms in vivo, are used in the prognosis of cardiovascular diseases and thus analyses of pulse waveform
Tomoki KITAWAKI, Masashi SHIMIZU
doaj +1 more source
Modelling the Fluid Mechanics of Cilia and Flagella in Reproduction and Development
, 2012 Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag anisotropy of
Blake, John R. +4 more
core +1 more source