Results 211 to 220 of about 4,431 (238)

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Mental health tracking among young Russians: practices and motivations. [PDF]

Discov Ment Health
Paramonova A, Mikhaylova O.
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Influence of Layer Thickness and Extrusion Temperature on the Mechanical Behavior of PLA-Flax TPMS Sandwich Structures Fabricated via Fused Filament Fabrication. [PDF]

Materials (Basel)
Marabello G, Chairi M, Parisi M, Di Bella G.   +3 more
europepmc   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Towards net zero land biotechnology: an assessment of biogenic feedstock potential for selected bioprocesses in Germany. [PDF]

Biotechnol Biofuels Bioprod
Tüllinghoff A, Sträuber H, Baleeiro FCF, Aurich A, Morejón MC, Meisel K, Cyffka KF, Harnisch F, Bühler K, Thrän D.   +9 more
europepmc   +1 more source

Exploring Outcome Measures for Mitochondrial Myopathies; Insights From a Longitudinal Study on TK2 Deficiency. [PDF]

J Inherit Metab Dis
Martín-Jimenez P, Bermejo-Guerrero L, Ochoa LE, Navarro-Riquelme M, Garrido-Moraga R, Hernández-Laín A, Hernández-Voth A, González Quintana A, Bermejo-Moriñigo A, González-Méndez V, Martín-Arriscado Arroba C, Smirnov D, Konstantinovskiy N, Arenas J, Martin MÁ, Blázquez A, Domínguez-González C.   +16 more
europepmc   +1 more source

Design of a Sensor-Based Digital Product Passport for Low-Tech Manufacturing: Traceability and Environmental Monitoring in Bio-Block Production. [PDF]

Sensors (Basel)
Pracucci A, Giovanardi M.
europepmc   +1 more source

Differential Measurement of Involuntary Breathing Movements. [PDF]

Biosensors (Basel)
Seman J, Rodriguez Amaro C, Tucker L, Fleury JM, Erickson K, White G, Santos TBR, Mellenthin MM.   +7 more
europepmc   +1 more source

B-73 Methods for Bio-logging primates

B-73 Methods for Bio-logging primates
openaire