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Frontiers in Immunology, 2023 IntroductionSulfavant A (SULF A) is a synthetic derivative of naturally occurring sulfolipids. The molecule triggers TREM2-related maturation of dendritic cells (DCs) and has shown promising adjuvant activity in a cancer vaccine model.Methodsthe ...
Giusi Barra +12 more
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Antitumor Potential of Immunomodulatory Natural Products
Marine Drugs, 2022 Cancer is one of the leading causes of death globally. Anticancer drugs aim to block tumor growth by killing cancerous cells in order to prevent tumor progression and metastasis.
Genoveffa Nuzzo +7 more
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UHPLC-MS Method for the Analysis of the Molecular Adjuvant Sulfavant A
Applied Sciences, 2021 A fast and sensitive method that is based on Ultra High Performance Liquid Chromatography coupled with High Resolution Mass Spectrometry (UHPLC-HRMS) for the measurement of Sulfavant A, a molecular adjuvant with a sulfolipid skeleton, is described.
Genoveffa Nuzzo +7 more
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Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy
Nature Communications, 2021 Induced motion has emerged as a method to increase the efficacy of delivery and therapeutic outcomes using nanomaterials. Here, the authors report on a Janus gold shell polymersome with aggregation-induced emission molecules for phototactic and ...
Shoupeng Cao +9 more
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Bio-Organic Chemistry Quarterly Report [PDF]
, 1961 This report is about the Absorption Spectra of spinach chloroplast fragments and the stability of the pigments.
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Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii [PDF]
, 2015 ACKNOWLEDGMENTS We acknowledge support from BBSRC grant no. BB/L009951/1, from the Scottish government Food, Land and People program, and from the Society for Applied Microbiology. E.A.B. is supported by a grant (no.
Bayer, Edward A. +11 more
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Amphiphilic AIEgen‐polymer aggregates: Design, self‐assembly and biomedical applications
Aggregate, 2022 Aggregation‐induced emission (AIE) is a phenomenon in which fluorescence is enhanced rather than quenched upon molecular assembly. AIE fluorogens (AIEgens) are flexible, conjugated systems that are limited in their dynamics when assembled, which improves
Shoupeng Cao +3 more
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Marine Drugs, 2020 Immunotherapy takes advantage of the immune system to prevent, control, and eliminate neoplastic cells. The research in the field has already led to major breakthroughs to treat cancer.
Carmela Gallo +9 more
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Identification of the Marine Alkaloid Lepadin A as Potential Inducer of Immunogenic Cell Death
Biomolecules, 2022 Natural products and their synthetic analogs and derivatives are a traditional source of bioactive molecules with potential development as drug candidates.
Genoveffa Nuzzo +13 more
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