Results 51 to 60 of about 412,242 (204)

Antigiardial activity of novel triazolyl quinolone-based chalcone derivatives: when oxygen makes the difference

Frontiers in Microbiology, 2015
Giardiasis is a common diarrheal disease worldwide caused by the protozoan parasite Giardia (G.) intestinalis. It is urgent to develop novel drugs to treat giardiasis, due to increasing clinical resistance to the gold standard drug metronidazole (MTZ ...
Vijay eBahadur, Daniela eMastronicola, Amit Kumar Singh, Hemandra Kumar Tiwari, Leopoldo Paolo Pucillo, Paolo eSarti, Brajendra Kumar Singh, Alessandro eGiuffre   +7 more
doaj   +1 more source

Drugs from Marine Sources

Applied Sciences, 2021
Throughout history, natural products have afforded a rich source of compounds that have found many applications in the fields of pharmacology [...]
Carmela Gallo, Genoveffa Nuzzo
doaj   +1 more source

A Century of Synthetic Fertilizer: 1909-2009 [PDF]

, 2009
This year marks a centenary of the synthetic fertilizer industry. German chemists, Fritz Haber and Carl Bosch, in 1909 demonstrated their industrial process for the manufacture of ammonia. The achievement won them accolades including Nobel Prizes.
Paull, John
core  

A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α

Journal of Lipid Research, 2015
The endocannabinoid 2-arachidonoylglycerol (2-AG) is predominantly biosynthesized by sn-1-diacylglycerol lipase α (DAGL-α) in the CNS. Selective inhibitors of DAGL-α will provide valuable insights in the role of 2-AG in endocannabinoid signaling ...
Tom van der Wel, Freek J. Janssen, Marc P. Baggelaar, Hui Deng, Hans den Dulk, Herman S. Overkleeft, Mario van der Stelt   +6 more
doaj   +1 more source

Facile Synthesis of Saikosaponins

Molecules, 2021
Saikosaponin A (SSa) and D (SSd) are typical oleanane-type saponins featuring a unique 13,28-epoxy-ether moiety at D ring of the aglycones, which exhibit a wide range of biological and pharmacological activities.
Ziqiang Wang, Bingcheng Wei, Tong Mu, Peng Xu, Biao Yu   +4 more
doaj   +1 more source

The vertical distribution of iron stable isotopes in the North Atlantic near Bermuda [PDF]

, 2012
Seawater dissolved iron isotope ratios (δ^(56)Fe) have been measured in the North Atlantic near Bermuda. In a full-depth profile, seawater dissolved δ^(56)Fe is isotopically heavy compared to crustal values throughout the water column (δ^(56)Fe_(IRMM-014)
Adkins, Jess, John, Seth G.
core   +1 more source

Chemical Synthesis of Marine-Derived Sulfoglycolipids, a New Class of Molecular Adjuvants

Marine Drugs, 2017
Vaccines play a primary role in the protection of human health by preventing infectious and chronic diseases. Recently we have reported 1,2-O-distearoyl-3-O-β-d-sulfoquinovosylglycerol (β-SQDG18), here named Sulfavant A (1), which shows promising ...
Emiliano Manzo, Laura Fioretto, Dario Pagano, Genoveffa Nuzzo, Carmela Gallo, Raffaele De Palma, Angelo Fontana   +6 more
doaj   +1 more source

The compositional and evolutionary logic of metabolism

, 2012
Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which layers of that ...
Alberts B, Andreini C, Balche W E, Barker H A, Benner S A, Berge C, Braakman R, Brazelton W J, Buss L W, Collins M D, Copley S D, Dagley S, Darwin C, de Duve C, Doyle J, Eric Smith, Erwin D H, Feist A M, Fenchel T, Fisher R A, Fry I, Gerhart J, Gesteland R F, Gould S J, Gray H B, Guiral M, Haldane J B S, Kallen R G, Kauffman S, Kim J, Lengeler J W, Ljungdahl L, MacKenzie R E, Martin W, Massey L K, Metzler D E, Morowitz H J, Morowitz H J, Morowitz H J, Nelson D L, Nitscke W, Odling-Smee F J, Oparin A I, Petsko G A, Puigbo P, Ragsdale S, Ragsdale S W, Rankama K, Razin S, Redfield A C, Redfield A C, Rogier Braakman, Russell M J, Schrödinger E, Schuster P, Segré D, Shapiro R, Simon H A, Simon H A, Smith E, Srinivasan V, Srinivasan V, Sterner R W, Stryer L, Szent-Gyorgyi A, Tazuya K, Utter M F, Vogels G D, von Wettstein D, Vorholt J A, Waber L J, Wald G, Wilson E B, Wächtershäuser G, Yarus M, Yi L   +75 more
core   +1 more source

Bio-Fertilizers via Co-Digestion: a Review [PDF]

, 2019
In diversifying the economies of most oil producing countries especially in regions with arable lands, Agriculture becomes the next choice aside mineral deposits.
Abdulkarim, Abdulwadud Yusuf, Abdulsalam, Surajudeen, El-Nafaty, Usman Aliyu, Muhammad, Idris Misau   +3 more
core   +2 more sources

The Janus effect of colloidal self-assembly on the biological response of amphiphilic drugs

Pharmacological Research
In aqueous environment amphiphilic molecules organize themselves into supramolecular structures deeply affecting the chemo-physical properties. Supramolecular assemby is also crucial in the pharmaceutical development of bioactive lipophilic molecules ...
Laura Fioretto, Marcello Ziaco, Marcello Mercogliano, Carmela Gallo, Genoveffa Nuzzo, Giuliana d’Ippolito, Daniela Castiglia, Angelo Fontana, Emiliano Manzo   +8 more
doaj   +1 more source