Results 201 to 210 of about 557,097 (227)

Insights into Bioactive Constituents from Pericarp of Garcinia mangostana: Anti-Inflammatory Effects via NF-κB/MAPK Modulation and M1/M2 Macrophage Polarization. [PDF]

Antioxidants (Basel)
Yang CS, Li SM, Chen JJ.
europepmc   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Recent Updates on Terpenoids and Other Bioactive Constituents of Marine Sponges. [PDF]

Molecules
Raymond MJF, Rakotondraibe HL.
europepmc   +1 more source

Nuciferine Suppresses Inflammatory Hepatocarcinogenesis by Targeting cPLA2‐Dependent Arachidonic Acid Metabolism

Advanced Science, EarlyView.
Nuciferine directly binds the C2 domain of cPLA2, impairing its Ca2+‐dependent membrane translocation and activation. By suppressing arachidonic acid release and downstream pro‐inflammatory eicosanoid production, nuciferine attenuates NF‐κB signaling and inflammatory hepatocarcinogenesis, revealing cPLA2 as a direct molecular target underlying its ...
Jing Sun, Xinyan Wu, Shuwei Luo, Yilang Liu, Jie Liu, Jun Lu, Weimin Wang, Xiao Feng, Tuo Zhang, Dipak Panigrahy, Jianjun Deng, Xiaojun Liao, Haixia Yang   +12 more
wiley   +1 more source

Dose-response assessment of neuroactive botanical extracts and their bioactive constituents using microelectrode array (MEA) recordings in rat primary cortical cultures. [PDF]

Pharm Biol
van Kleef RGDM, Wopken JP, Krzykwa J, Mitchell CA, Westerink RHS.   +4 more
europepmc   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Changes in Bioactive Constituents in Black Rice Metabolites Under Different Processing Treatments. [PDF]

Foods
Hong B, Zhang S, Yuan D, Shan S, Zhang JY, Sha DX, Chen DP, Yin WW, Lu SW, Ren CY.   +9 more
europepmc   +1 more source

Effects of photosynthetic properties, soil environment and bioactive constituents of Eucommia ulmoides Oliver under two planting models. [PDF]

BMC Plant Biol
Zhang GZ, Jiang WH, Zhu YH, Sun GT, Xu H, Zhu MQ.   +5 more
europepmc   +1 more source

Immunomodulatory Activities of Thai Herbs and the Druggability of Their Bioactive Constituents: A Comprehensive Review for Potential Phytopharmaceutical Product Development. [PDF]

Drug Des Devel Ther
Boonyarattanasoonthorn T, Raksapatcharawong A, Junsaeng D, Suknuntha K, Puttanawarut C, Khemawoot P.   +5 more
europepmc   +1 more source

[Screening of potential bioactive constituents in wall-broken <i>Ganoderma lucidum</i> spore powder for promoting ulcer healing]. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi
Liu J, Wang J, Li Y, Cong Y, Guan X.
europepmc   +1 more source