Results 61 to 70 of about 557,097 (227)

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

Advanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye, Xuanzhe Liu, Zifan Pei, Chenyi Jiang, Xiaofen Zhang, Lin Lin, Qihang Fang, Binyu Chen, Longxiang Shen, Liang Cheng, Peng Ding, Xianyou Zheng   +11 more
wiley   +1 more source

Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering

Advanced Materials Interfaces, EarlyView.
A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser, Jiranuwat Sapudom, Sotiris Psilodimitrakopoulos, Emmanuel Stratakis, Jeremy Teo, Vincent Chan, Charalampos Pitsalidis   +6 more
wiley   +1 more source

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science
Enfumafungin‐type antibiotics, represented by enfumafungin and fuscoatroside, constitute a distinct class of fungi‐derived fernane‐type triterpenoids renowned for their potent antifungal activity.
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
doaj   +1 more source

3D Printing of Self‐Healing Polymers by Material Extrusion: A Process‐Centric Review of Setups, Parameters, and Applications

Advanced Robotics Research, EarlyView.
This review highlights recent advances in material extrusion 3D printing of self‐healing polymers, focusing on the interplay between material chemistry, rheology, hardware customization, and process optimization. Filament‐ and ink‐based extrusion strategies, multimaterial architectures, and postprocessing approaches are discussed for applications in ...
Antonio Pavone, Gianni Stano, Gianluca Percoco   +2 more
wiley   +1 more source

Autonomous Navigation of Pollen‐Inspired Magnetic Microrobots for Biomedical Applications

Advanced Robotics Research, EarlyView.
A sunflower pollen‐inspired magnetic microrobot enables controlled rolling navigation in vessel‐like environments. Its open geometry reduces hydrodynamic drag, while vision‐based closed‐loop control, shortest‐path planning, and reinforcement learning support target‐reaching and maze navigation with microrobot‐scale accuracy, highlighting a route toward
Ali Anil Demircali, Abdurrahim Yilmaz, Meysam Keshavarz, Jinshi Zhao, Ara Darzi, Eric Yeatman, Burak Temelkuran   +6 more
wiley   +1 more source

Goji berry-derived phenylpropionyl phenylethylamine derivatives protect against ethanol-induced hepatic damage

Food Science and Human Wellness
Goji berry is a famous edible and medicinal substance around the world. In this research, 15 phenylpropionyl phenylethylamine derivatives (1−15), in cluding one new compound (1), were separated and identified from g oji berry.
Zhengqun Zhou, Zhaodi Che, Jiancong Mai, Rui Zhang, Zhihui Luo, Yifang Li, Kwokfai So, Jia Xiao, Xinsheng Yao, Hao Gao   +9 more
doaj   +1 more source

Advances in chemical constituents and quality control of turmeric

World Journal of Traditional Chinese Medicine, 2019
Turmeric, derived from the rhizomes of Curcuma longa L. (Zingiberaceae), is one of the most popular herbal medicines. Its main bioactive constituents include curcuminoids, sesquiterpenes, and terpecurcumins.
Zhan-Peng Shang, Lu-Lu Xu, Ying-Ying Lu, Meng Guan, De-Yun Li, Zhi-Yong Le, Zong-Li Bai, Xue Qiao, Min Ye   +8 more
doaj   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Facet-dependent effect of engineered nanoceria on dopaminergic neurotoxicity and motor deficits involving glutathione depletion

Ecotoxicology and Environmental Safety
Cerium dioxide (CeO 2 ) nanoparticles (NPs), bearing the switchable Ce 3+ /Ce 4+ redox pair, are attractive for applications in green energy and other fields. However, their potential toxicity, especially to the nervous system, remains poorly understood.
Zhang Zhang, Chaoqun Wang, Yan Pan, Yuanyuan Song, Xiaohe Han, Jun Yang, Juan Liu, Zhifeng Huang, Ken Kin-Lam Yung, Lei Shi, Zicong Tan, Shiqing Zhang, Kaili Lin   +12 more
doaj   +1 more source

Cleistenolide and Cleistodienol: Novel Bioactive Constituents of

Natural Product Communications, 2007
(-)-5-Acetoxy-6-(1-benzoyloxy-2-acetoxyethyl)-pyr-3-en-2-one (cleistenolide) and (-)-2,6-diacetoxy-5-hydroxy-cyclohex-3-enylidenemethyl benzoate (cleistodienol) were isolated as novel antimicrobial and cytotoxic constituents of Cleistochlamys kirkii ...
Stephen Samwel, Stephen J.M. Mdachi, Mayunga H.H. Nkunya, Beatrice N. Irungu, Mainen J. Moshi, Brian Moulton, Brian S. Luisi   +6 more
doaj   +1 more source