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Bioactivity evolution of the surface functionalized bioactive glasses
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014AbstractThe formation of a calcium phosphate layer on the surface of the SiO2–CaO–P2O5 glasses after immersion in simulated body fluid (SBF) generally demonstrates the bioactivity of these materials. Grafting of the surface by chemical bonding can minimize the structural changes in protein adsorbed on the surface.
Klára, Magyari +5 more
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Bioactive Glass Three Decades On
Journal of Long-Term Effects of Medical Implants, 2005Bioglasses were first introduced in the early 1970s and since have found wide use in dentistry. The original 45S5 bioglass, as described by Hench, is a silica-based melt-derived glass characterized by a Si02 content of less than 60%, a high Na2O and CaO content, and a high CaO:P2O5 ratio.
Mark V, Thomas +2 more
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Bioactive glass coatings: A review
Surface Engineering, 2011Bioactive glasses, discovered by Hench and co-workers at the end of the 1960s, are among the most promising biomaterials for bone repair and reconstruction, mainly thanks to their high bioactivity index. Unfortunately, due to their brittleness and relatively poor mechanical properties, their clinical applications are limited to non-load bearing ...
SOLA, Antonella +3 more
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Carbonate Formation on Bioactive Glasses
Langmuir, 2004The system termed 58S is a sol-gel-synthesized bioactive glass composed of SiO2, CaO, and P2O5, used in medicine as bone prosthetic because, when immersed in a physiological fluid, a layer of hydroxycarbonate apatite is formed on its surface.
Marta, Cerruti, Claudio, Morterra
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Interaction of bioactive glass with clodronate
International Journal of Pharmaceutics, 2013Bone tissue engineering is a rapidly growing area of research involving the use of bioactive glass (BG) alone and in combination with different materials. The objective of this study was to investigate the interaction of BG with clodronate. Characterisation of the interaction between BG and clodronate was undertaken using; scanning electron microscopy (
Kirsi, Rosenqvist +4 more
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Bioactive glasses entering the mainstream
Drug Discovery Today, 2018Over the past decade, the extended research on bioactive glasses (BGs) has drastically grown because of their bioactive nature and unique ability to deliver therapeutics in tissue engineering, regenerative medicine and even cancer research. These strategies mostly rely on the inherent potential of BGs regarding bonding to the living tissues and ...
Kargozar, Saeid +4 more
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Bioactive Glasses and Glass-Ceramics
Materials Science Forum, 1998Volume I: Bioactive Glasses and Glass-Ceramics General Science and Development Composities and Coatings Tissue and Organ Culture Studies Preclinical and Clinical Results ...
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Bioactive Glasses—Structure and Properties
Angewandte Chemie International Edition, 2015AbstractBioactive glasses were the first synthetic materials to show bonding to bone, and they are successfully used for bone regeneration. They can degrade in the body at a rate matching that of bone formation, and through a combination of apatite crystallization on their surface and ion release they stimulate bone cell proliferation, which results in
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ANGIOGENIC POTENTIAL OF BIOACTIVE GLASSES
2013Enhancement of the angiogenic potential of implantable tissue scaffolds is the focus of considerable research efforts in tissue engineering (TE) strategies. 1–3 Angiogenesis, the formation of new blood vessels from the endothelium of the existing vasculature, plays a pivotal role in TE and wound healing.
Gorustovich Alonso, Alejandro Adrian +3 more
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