Results 121 to 130 of about 19,030 (297)

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Adipose Stem Cell Response to Borophosphate Bioactive Glass

open access: yesApplied Sciences
Silicate and borate bioactive glasses have been reported to create alkaline conditions by rapidly releasing ions when reacting in aqueous solution. At certain levels, this alkaline solution can negatively affect cell viability.
Nada A. Abokefa   +5 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

open access: yesAdvanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar   +15 more
wiley   +1 more source

Surface Modification of Biodegradable Porous Mg Bone Scaffold Using Polycaprolactone/Bioactive Glass Composite [PDF]

open access: yes, 2015
A reduction in the degradation rate of magnesium (Mg) and its alloys is in high demand to enable these materials to be used in orthopedic applications. For this purpose, in this paper, a biocompatible polymeric layer reinforced with a bioactive ceramic ...
Razavi, Mehdi   +3 more
core   +1 more source

Perspectives on the impact of crystallization in bioactive glasses and glass‐ceramics

open access: yesInternational Journal of Ceramic Engineering & Science
Both unwanted and induced crystallization can impact bioactivity, physical and mechanical properties of bioactive glasses (BGs). Uncontrolled crystallization has negative consequences, rendering BGs unreliable.
Maziar Montazerian   +2 more
doaj   +1 more source

Sea Urchin‐Inspired Immuno‐Instructive Ionic Flow Drives MSCs‐Macrophage Communication to Promote Bone Regeneration

open access: yesAdvanced Materials, EarlyView.
ABSTRACT Bone tissue regeneration is a complex physiological process dependent on the spatiotemporal coordination of immune cells and stem cells. Conventional research primarily elucidates the mechanism through which materials facilitate bone formation by initially modulating macrophages and subsequently encouraging the osteogenic differentiation of ...
Yang Lu   +11 more
wiley   +1 more source

Exploring the potential of In situ radiopaque bioactive glass in modern biomedical application-scope unforeseen

open access: yesMedicine in Novel Technology and Devices
In-situ radiopaque bioactive glasses (RBG’s) have emerged as a significant advancement in biomedical applications, combining the regenerative properties of bioactive glasses with enhanced visuality under imaging modalities (X-ray, micro-CT, fluoroscopy ...
Rupam Saha, Jui Chakraborty
doaj   +1 more source

Cell Adhesion by Design: Engineering Tissue Culture Scaffolds With Adhesion Cues

open access: yesAdvanced Materials Interfaces, EarlyView.
ABSTRACT In scaffold‐based tissue engineering, the matrix should provide adequate adhesion cues for cell attachment, spreading, and function. Given the multitude of adhesion receptors and the diversity of scaffolds, there are many approaches to render scaffolds adhesive, even though they are not all equivalent.
Dalia Dranseike   +3 more
wiley   +1 more source

Corrosion mechanism and bioactivity of borate glasses analogue to Hench’s bioglass [PDF]

open access: yesProcessing and Application of Ceramics, 2012
Bioactive borate glasses (from the system Na2O-CaO-B2O3-P2O5) and corresponding glass-ceramics as a new class of scaffold material were prepared by full replacement of SiO2 with B2O3 in Hench patented bioactive glass.
Mona A. Ouis   +2 more
doaj  

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