Results 21 to 30 of about 18,395 (198)

Sensitive and specific quantification of antisense oligonucleotides using probe alteration-linked self-assembly reaction technology

BioTechniques, 2023
Quantitative bioanalysis is essential when establishing pharmacokinetic properties during the drug development process. To overcome challenges of sensitivity, specificity and process complexity associated with the conventional analysis of antisense ...
Masako Osawa, Takurou Akiya, Funa Ogawa, Takao Suzuki, Masaki Yamagami, Tadashi Umemoto, Akira Ideno   +6 more
doaj   +1 more source

Abnormal Anionic Porphyrin Sensing Effect for HER2 Gene Related DNA Detection via Impedance Difference between MWCNTs and Single-Stranded DNA or Double-Stranded DNA

Molecules, 2018
Human epidermal growth factor receptor 2 (HER2) is a key tumor marker for several common and deadly cancers. It is of great importance to develop efficient detection methods for its over-expression. In this work, an electrochemical impedance spectroscopy
Jingheng Ning, Long Liu, Xin Luo, Min Wang, Donglin Liu, Rong Hou, Donger Chen, Jianhui Wang   +7 more
doaj   +1 more source

SAMPLE PREPARATION AND BIOANALYSIS VALIDATION FOR NATURAL PRODUCT SAMPLE [PDF]

, 2021
Bioanalysis study and its validation are important for the application in natural drug discovery and preparation for natural medicine products with safe drug development approaches.
AYUMIATI, IDA, SAPUTRI, FEBRINA AMELIA, MUCHTARIDI, MUCHTARIDI   +2 more
core   +1 more source

Magnetic Bead—Magic Bullet

Micromachines, 2016
Microfluidics is assumed to be one of the leading and most promising areas of research since the early 1990s. In microfluidic systems, small spherical magnetic particles with superparamagnetic properties, called magnetic beads, play an important role in ...
Christine Ruffert
doaj   +1 more source

Bioluminescence Resonance Energy Transfer in Bioanalysis

, 2006
This chapter contains sections titled: Introduction BRET Principle, Efficiency, and Instrumentation Comparison of BRET and FRET Examples of BRET Donor–Acceptor Pairs Applications of BRET in Bioanalysis Homogeneous Assays Protein–Protein Interactions and ...
Deo, Sapna K, Shrestha, Suresh, Sapna K. Deo, Suresh Shrestha   +3 more
core   +1 more source

Cascade Amplifying Electrochemical Bioanalysis for Zearalenone Detection in Agricultural Products: Utilizing a Glucose–Fenton–HQ System on Bimetallic–ZIF@CNP Nanocomposites

Foods
The integration of advanced materials and signaling cascade strategies is a promising and highly relevant topic for enhancing the performance of bioanalysis. In this study, a three-stage cascade amplification electrochemical bioanalysis (TCAE-bioanalysis)
Guoxing Liu, Zhaoying Liu, Yumeng Sun, Mingna Sun, Jinsheng Duan, Ye Tian, Daolin Du, Ming Li   +7 more
doaj   +1 more source

Bioanalytical HPLC Applications of In-Tube Solid Phase Microextraction: A Two-Decade Overview

Molecules, 2020
In-tube solid phase microextraction is a cutting-edge sample treatment technique offering significant advantages in terms of miniaturization, green character, automation, and preconcentration prior to analysis.
Natalia Manousi, Paraskevas D. Tzanavaras, Constantinos K. Zacharis   +2 more
doaj   +1 more source

Metabolite Bioanalysis in Drug Development: Recommendations from the IQ Consortium Metabolite Bioanalysis Working Group

, 2023
The intent of this perspective is to share the recommendations of the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ Consortium) Metabolite Bioanalysis Working Group (WG) on the fit-for-purpose metabolite ...
Winter, Serge, Li, Wenkui, Cuyckens, Filip, Fraier, Daniela, Liang, Yuexia, Pedersen, Mette L., Spracklin, Douglas K., Xu, Xiaohui (Sophia), Boer, Jason, Wagner, David S., Lu, Ding, Dear, Gordon, Mangus, Heidi, Vazvaei-Smith, Faye, Moliner, Patricia, Romeo, Andrea A.   +15 more
core   +1 more source

Skin biosensing and bioanalysis: what the future holds

Precision Nanomedicine, 2018
Wearable skin biosensors have important applications in health monitoring, medical treatment and theranostics. There has been a rapid growth in the development of novel biosensing and bioanalytical techniques in recent years, much of it underpinned by ...
S, Moein Moghimi, Keng Wooi Ng
doaj   +1 more source

Recent developments and applications of polymer monolithic stationary phases

Analytical Science Advances, 2021
This review highlights the current trends and the most recent advances in the field of preparation and application of organic polymer‐based monolithic materials and covers literature published in 2020.
Sebastiaan Eeltink, Daniel Meston, Frantisek Svec   +2 more
doaj   +1 more source