Results 111 to 120 of about 296,429 (339)

Antiproliferation, 3D-multicellular spheroid and VEGFR-2 inhibitory properties of spiroindolin-2-ones with phosphonate function

Scientific Reports
Spiroindolin-2-ones with phosphonate function 17a‒t (20 analogs, 96‒72% yield) were generated by microwave synthetic methodology using azomethine cycloaddition of the appropriate 3,5-bis(ylidene)-4-piperidone-1-phosphonate 14a‒g.
Sara M. Hassan, Alyaa Farid, Mohamed S. Bekheit, Siva S. Panda, Benson M. Kariuki, Anwar Abdelnaser, Soad Nasr, Walid Fayad, May A. El-Manawaty, Ahmed A. F. Soliman, Adel S. Girgis   +10 more
doaj   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, EarlyView.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source

A Cell-Based Potency Assay for Determining the Relative Potency of Botulinum Neurotoxin A Preparations Using Manual and Semi-Automated Procedures

Toxins
Cell-based potency assays (CBPAs) are required for the potency testing and commercial release of botulinum neurotoxin (BoNT)-based drug products. These CBPAs must account for the toxin’s biological activities while meeting regulatory guidelines for ...
F. Mark Dunning, Sara Hendrickson, Serena Wolfe, Dan Harding, Theresa Geurs, Timothy M. Piazza, Thomas A. Little, Ward C. Tucker   +7 more
doaj   +1 more source

Outlining the Potential Role of Humic Products in Modifying Biological Properties of the Soil—A Review

Frontiers in Environmental Science, 2019
There is a growing awareness among farmers about the importance of soil for sustaining crop production and soil health. Marked interests in “environmentally-friendly” soil fertilization in agriculture has attracted significant attention in the last ...
Maria Pukalchik, Kamila Kydralieva, Kamila Kydralieva, Olga Yakimenko, Elena Fedoseeva, Elena Fedoseeva, Vera Terekhova, Vera Terekhova   +7 more
doaj   +1 more source

Screening of Irish Fruit and Vegetable Germplasm for Novel Anti-tumour and Pesticidal Compounds [PDF]

, 2012
Conference paperPhytochemicals are a rich source of novel therapeutic and insecticidal agents (McLaughlin and Chang, 1999). Considerable research effort has been directed at screening exotic and medicinal plants in the search for novel products. However,
Alqudah, J.M. I., Barry-Ryan, Catherine, Gaffney, Michael, Martin-Diana, A. B., Reilly, Kim   +4 more
core  

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens

Environmental Health Perspectives, 2008
Background Concerns have been raised about the biological and toxicologic effects of the antimicrobials triclocarban (TCC) and triclosan (TCS) in personal care products.
K. Ahn, Bin Zhao, Jiangang Chen, G. Cherednichenko, Enio Sanmarti, M. Denison, B. Lasley, I. Pessah, D. Kültz, D. Chang, S. Gee, B. Hammock   +11 more
semanticscholar   +1 more source

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk, Ewa Dziewięcka, Sylwia Wiśniowska‐Śmiałek, Agnieszka Stępień, Katarzyna Graczyk, Agata Leśniak‐Sobelga, Marta Hlawaty, Jakub Woźniak, Maryia Savitskaya, Katarzyna Holcman, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś   +12 more
wiley   +1 more source

Differential sensitivity of locally naturalized Panicum species to 4-hydroxyphenyl pyruvate dioxygenase and acetolactate synthase-inhibiting herbicides

Julius-Kühn-Archiv, 2014
One of the possible reasons for the expansion of the alien panicoid grasses Panicum schinzii (Transvaal millet), Panicum dichotomiflorum (Fall panicum) and Panicum capillare (Witchgrass) in maize fields in Belgium might be a lower sensitivity to post ...
De Cauwer, Benny, Geeroms, Tim, Claerhout, Sofie, Reheul, Dirk, Bulcke, Robert   +4 more
doaj   +1 more source

Evaluation of the susceptibility of the pea aphid, Acyrthosiphon pisum, to a selection of novel biorational insecticides using an artificial diet [PDF]

, 2009
An improved technique was developed to assay the toxicity of insecticides against aphids using an artificial diet. The susceptibility of the pea aphid Acyrthosiphon pisum (Harris) (Hemiptera: Aphidoidea) was determined for a selection of novel ...
Sadeghi, Amin, Smagghe, Guy, Van Damme, Els   +2 more
core   +3 more sources