Results 81 to 90 of about 296,429 (339)

Profiling Animal Toxicants by Automatically Mining Public Bioassay Data: A Big Data Approach for Computational Toxicology

PLoS ONE, 2014
In vitro bioassays have been developed and are currently being evaluated as potential alternatives to traditional animal toxicity models. Already, the progress of high throughput screening techniques has resulted in an enormous amount of publicly ...
Jun Zhang, J. Hsieh, Hao Zhu
semanticscholar   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, EarlyView.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source

Development and calibration of a portable detection device for in vivo measurement of high-energy photon emitters incorporated by humans

Brazilian Journal of Radiation Sciences, 2018
This work presents the evaluation of the applicability and sensitivity of a portable detection device specially designed for in vivo measurement of high-energy photon emitters in the human body.
Alexandre Barbosa Soares, Mayara Nascimento Arbach, Éder Augusto de Lucena, Ana Letícia Almeida Dantas, Bernardo Maranhão Dantas   +4 more
doaj   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

Advanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang, SiYu Xv, Chao Wu, Nan Li, GuoPeng Teng, XuePing Huang, Jian Luo   +6 more
wiley   +1 more source

Assessment of cytotoxicity of some synthetic compounds against breast carcinoma spheroids with subsequent analysis of pro-apoptotic and gene expression

Scientific Reports
The current study examined the anticancer potential of 80 synthetic organic compounds at 50µM using in vitro two-dimensional (2D) and three-dimensional (3D) spheroids model breast adenocarcinoma (MCF7) models.
Khaled Mahmoud, Elham M. Youssef, Farid M. Sroor, Walid Fayad   +3 more
doaj   +1 more source

Using UPLC–MS/MS to Evaluate the Dissemination of Pyriproxyfen by Aedes Mosquitoes to Combat Cryptic Larval Habitats after Source Reduction in Kaohsiung in Southern Taiwan

Insects, 2020
The policy regarding mosquito control strategies in Taiwan is based on integrated vector management (IVM). The major approach is source reduction via collaboration by both residents and governments.
Ying-An Chen, Yi-Ting Lai, Kuo-Chih Wu, Tsai-Ying Yen, Chia-Yang Chen, Kun-Hsien Tsai   +5 more
doaj   +1 more source

An examination of the putative glucose tolerance factor activity of amino acid and peptide fractions isolated from brewer's yeast : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]

, 1985
The first report of the possible existance of a glucose tolerance factor (GTF) was made by Mertz and Schwarz (1955) who noticed that a dietary additive, termed factor 3, isolated from an enzymatic casein hydrolysate (Schwarz (1952)), maintained normal ...
Jackson, Timothy Graham
core  

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source

Asn12 and Asn278: Critical Residues for In Vitro Biological Activity of Reteplase

Advances in Hematology, 2010
Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome.
Naganath Mandi, Kalyana R. Sundaram, Sunil K. Tandra, Suman Bandyopadhyay, Sriram Padmanabhan   +4 more
doaj   +1 more source

The potential of biological soil disinfestation to manage Fusarium foot and root rot in Asparagus [PDF]

, 2008
In a field experiment on an abandoned asparagus field we studied the effect of Biological Soil Disinfestation (BSD) on survival of buried inoculum samples of three test pathogens (Fusarium redolens f.sp.
Blok, W.J., Coenen, G.C.M., Lamers, J.G., Termorshuizen, A.J.   +3 more
core   +2 more sources