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The fate of flavonoids after oral administration: a comprehensive overview of its bioavailability
Critical reviews in food science and nutrition, 2021Despite advancements in synthetic chemistry, nature remains the primary source of drug discovery, and this never-ending task of finding novel and active drug molecules will continue.
Abid Naeem +11 more
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Bioavailability of isoflavones
Journal of Chromatography B, 2002Isoflavones are disease protective components of soybeans. Isoflavone metabolism and bioavailability are key to understanding their biological effects. Isoflavone glucuronides, dominant biotransformation products in humans that are more hydrophilic than isoflavone aglycones, activate human natural killer cells in vitro but are less toxic to NK cells ...
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The bioavailability of phenytoin
Journal of Neurology, 1977The bioavailability of three commercial products of phenytoin (Epanutin, sodium salt; Phenhydan, calcium salt; Zentropil, free acid) was studied relative to a standard solution of sodium phenytoin. Each preparation was given for 14 days in a daily dose of 300 mg according to a cross over design.
G. Hildenbrand +3 more
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Acta Endocrinologica, 1982
Abstract. A rapid radioimmunoassay, using a specific antiserum against oestriol (Oe3) was developed for the analyses of unconjugated oestriol in post-menopausal women before and after oral administration of oestriol. One ml plasma was extracted once with 10 ml diethyl ether and assayed without further purification. The plasma levels of oestriol in post-
Elof D. B. Johansson +2 more
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Abstract. A rapid radioimmunoassay, using a specific antiserum against oestriol (Oe3) was developed for the analyses of unconjugated oestriol in post-menopausal women before and after oral administration of oestriol. One ml plasma was extracted once with 10 ml diethyl ether and assayed without further purification. The plasma levels of oestriol in post-
Elof D. B. Johansson +2 more
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Bioavailability of anthocyanins
Drug Metabolism Reviews, 2014Anthocyanins are a subgroup of flavonoids responsible for the blue, purple, and red color of many fruits, flowers, and leaves. Consumption of foods rich in anthocyanins has been associated with a reduced risk of cardiovascular disease and cancer. The fate of anthocyanins after oral administration follows a unique pattern rather different from those of ...
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2010
Soil ingestion is a key exposure pathway in Human Health Risk Assessment for contaminants in soil. The theory and mechanisms of how contaminants in a soil enter the human body through the gastrointestinal tract are outlined. The methods available for measuring human exposure using human, animal and validated in-vitro laboratory methods are described ...
Cave, Mark +4 more
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Soil ingestion is a key exposure pathway in Human Health Risk Assessment for contaminants in soil. The theory and mechanisms of how contaminants in a soil enter the human body through the gastrointestinal tract are outlined. The methods available for measuring human exposure using human, animal and validated in-vitro laboratory methods are described ...
Cave, Mark +4 more
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Dietary flavonoids: bioavailability, metabolic effects, and safety.
Annual review of nutrition, 2002Flavonoids comprise the most common group of plant polyphenols and provide much of the flavor and color to fruits and vegetables. More than 5000 different flavonoids have been described.
J. Ross, Christine M. Kasum
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Polyphenols and bioavailability: an update
Critical reviews in food science and nutrition, 2019Based on many cell culture, animal and human studies, it is well known that the most challenge issue for developing polyphenolics as chemoprevention or anti-diabtetic agents is the low oral bioavailability, which may be the major reason relating to its ...
Hui Teng, Lei Chen
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Bioavailability of Soil-Bound TCDD: Oral Bioavailability in the Rat
Toxicological Sciences, 1988The implications to the public health of trace amounts of 2,3,7,8-TCDD in the environment are under evaluation by regulatory agencies in the United States and Western Europe. One major consideration in such evaluations is the contribution to human exposure via ingestion of TCDD-contaminated soil.
H, Shu +7 more
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