Results 1 to 10 of about 203,957 (262)
Cell-Penetrating Peptide-Surface Modified Liposomes to Enhance the Intestinal Absorption of Enoxaparin [PDF]
Pharmaceutical Sciences, 2023 Background: Enoxaparin is low-molecular-weight heparin administered by subcutaneous/intravenous injection. The oral bioavailability of enoxaparin is restricted by its low absorption through the intestine.
Hessam Rostamian +4 more
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Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery
Pharmaceutics, 2022 Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration.
Rong Lu +4 more
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Effect of Cosolvents on the Absorptive Clearance of Ketotifen Fumarate from Rabbit Intestine, In-situ [PDF]
Journal of Advanced Pharmacy Research, 2018 Objective: Investigate the effect of ethanol, polyethylene glycol 400, propylene glycol, glycerol and sorbitol on the absorptive clearance of ketotifen fumarate in the rabbit.
Sanaa El-Gizawy +2 more
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Application Research Progress of Intestinal Organoids in Nutrient Absorption
Shipin gongye ke-ji, 2022 The intestinal tract is not only the main part of nutrient digestion and absorption, but also an important immune and endocrine organ. The digestion and absorption of nutrients in the intestine is a crucial factor to achieve their efficient utilization ...
Yaxuan PENG +7 more
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Intestinal Absorption of Fructose [PDF]
Annual Review of Nutrition, 2018 Increased understanding of fructose metabolism, which begins with uptake via the intestine, is important because fructose now constitutes a physiologically significant portion of human diets and is associated with increased incidence of certain cancers and metabolic diseases.
Ronaldo P, Ferraris +2 more
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Self‐Healing Hydrogels: The Next Paradigm Shift in Tissue Engineering?
Advanced Science, 2019 Given their durability and long‐term stability, self‐healable hydrogels have, in the past few years, emerged as promising replacements for the many brittle hydrogels currently being used in preclinical or clinical trials. To this end, the incompatibility
Sepehr Talebian +10 more
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Recent Advances in the Gastrointestinal Complex in Vitro Model for ADME Studies
Pharmaceutics, 2023 Intestinal absorption is a complex process involving the permeability of the epithelial barrier, efflux transporter activity, and intestinal metabolism.
Kazuyoshi Michiba +3 more
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Pharmacology Research & Perspectives, 2020 Prediction of the intestinal absorption of new chemical entities (NCEs) is still difficult, in part because drug efflux transporters, including breast cancer resistance protein (BCRP) and P‐glycoprotein (P‐gp), restrict their intestinal permeability.
Iichiro Kawahara +4 more
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Development of active jejunal glucose absorption in broiler chickens
Poultry Science, 2023 : Growth in chickens, especially meat-type chickens (broilers), is extremely rapid, but studies on the regulatory mechanism of intestinal glucose absorption with growth are few, contradictory, and unclear.
Mikako Shibata +4 more
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Frontiers in Physiology, 2023 Background: The steady-state intestinal perfusion system represents a tool used in measuring intestinal fluid absorption and bicarbonate secretion in vivo; however, detailed procedures and parameters were not elucidated fully.Aim: We focused on the ...
Wenjuan Fan, Qinghai Tan
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