Results 21 to 30 of about 3,856,202 (336)
Cell-Penetrating Peptide-Surface Modified Liposomes to Enhance the Intestinal Absorption of Enoxaparin [PDF]
Pharmaceutical Sciences, 2023 Background: Enoxaparin is low-molecular-weight heparin administered by subcutaneous/intravenous injection. The oral bioavailability of enoxaparin is restricted by its low absorption through the intestine.
Hessam Rostamian +4 more
doaj +1 more source
In vitro Bioaccessibility and Intestinal Absorption of Selected Bioactive Compounds in Terminalia ferdinandiana. [PDF]
Front Nutr, 2021 Terminalia ferdinandiana (or Kakadu plum), a native Australian fruit with potential health benefits, contains bioactive compounds such as ellagic acid (EA), ascorbic acid (AA) and calcium, and antinutrients such as oxalic acid (OA). However, few is known
Akter S +6 more
europepmc +2 more sources
Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery
Pharmaceutics, 2022 Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration.
Rong Lu +4 more
doaj +1 more source
Dietary Fructose Improves Intestinal Cell Survival and Nutrient Absorption
Nature, 2021 Fructose consumption is linked to the rising incidence of obesity and cancer, which are two of the leading causes of morbidity and mortality globally1,2.
Samuel R. Taylor +17 more
semanticscholar +1 more source
Effect of Cosolvents on the Absorptive Clearance of Ketotifen Fumarate from Rabbit Intestine, In-situ [PDF]
Journal of Advanced Pharmacy Research, 2018 Objective: Investigate the effect of ethanol, polyethylene glycol 400, propylene glycol, glycerol and sorbitol on the absorptive clearance of ketotifen fumarate in the rabbit.
Sanaa El-Gizawy +2 more
doaj +1 more source
Application Research Progress of Intestinal Organoids in Nutrient Absorption
Shipin gongye ke-ji, 2022 The intestinal tract is not only the main part of nutrient digestion and absorption, but also an important immune and endocrine organ. The digestion and absorption of nutrients in the intestine is a crucial factor to achieve their efficient utilization ...
Yaxuan PENG +7 more
doaj +1 more source
Journal of Controlled Release, 2021 Absorption, distribution, metabolism and excretion (ADME) studies represent a fundamental step in the early stages of drug discovery. In particular, the absorption of orally administered drugs, which occurs at the intestinal level, has gained attention ...
Arianna Fedi +5 more
semanticscholar +1 more source
Pharmaceutics, 2020 The systematic separation strategy has long and widely been applied in the research and development of herbal medicines. However, the pharmacological effects of many bioactive constituents are much weaker than those of the corresponding herbal extracts ...
Qing Zhao +6 more
semanticscholar +1 more source
Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα
Nature Communications, 2021 Intestinal surface changes in size and function, but what propels these alterations and what are their metabolic consequences is unknown. Here we report that the food amount is a positive determinant of the gut surface area contributing to an increased ...
O. Stojanović +10 more
semanticscholar +1 more source
Intestinal barrier function and absorption in pigs after waeaning: a review [PDF]
, 2011 Under commercial conditions, weaning of piglets is associated with social, environmental and dietary stress. Consequently, small-intestinal barrier and absorptive functions deteriorate within a short time after weaning.
Wijtten, P.J.A. +2 more
core +1 more source