Results 311 to 320 of about 596,432 (340)
Journal of Medicinal Chemistry, 2005 Responding to a demonstrated need for scientists to forecast the permeability and bioavailability (F) properties of compounds before their purchase, synthesis, or advanced testing, we have developed a score that assigns the probability that a compound will have F > 10% in the rat.
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Bioavailability of isoflavones
Journal of Chromatography B, 2002Isoflavones are disease protective components of soybeans. Isoflavone metabolism and bioavailability are key to understanding their biological effects. Isoflavone glucuronides, dominant biotransformation products in humans that are more hydrophilic than isoflavone aglycones, activate human natural killer cells in vitro but are less toxic to NK cells ...
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The bioavailability of phenytoin
Journal of Neurology, 1977The bioavailability of three commercial products of phenytoin (Epanutin, sodium salt; Phenhydan, calcium salt; Zentropil, free acid) was studied relative to a standard solution of sodium phenytoin. Each preparation was given for 14 days in a daily dose of 300 mg according to a cross over design.
G. Hildenbrand +3 more
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Acta Endocrinologica, 1982
Abstract. A rapid radioimmunoassay, using a specific antiserum against oestriol (Oe3) was developed for the analyses of unconjugated oestriol in post-menopausal women before and after oral administration of oestriol. One ml plasma was extracted once with 10 ml diethyl ether and assayed without further purification. The plasma levels of oestriol in post-
Elof D. B. Johansson +2 more
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Abstract. A rapid radioimmunoassay, using a specific antiserum against oestriol (Oe3) was developed for the analyses of unconjugated oestriol in post-menopausal women before and after oral administration of oestriol. One ml plasma was extracted once with 10 ml diethyl ether and assayed without further purification. The plasma levels of oestriol in post-
Elof D. B. Johansson +2 more
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2010
Soil ingestion is a key exposure pathway in Human Health Risk Assessment for contaminants in soil. The theory and mechanisms of how contaminants in a soil enter the human body through the gastrointestinal tract are outlined. The methods available for measuring human exposure using human, animal and validated in-vitro laboratory methods are described ...
Cave, Mark +4 more
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Soil ingestion is a key exposure pathway in Human Health Risk Assessment for contaminants in soil. The theory and mechanisms of how contaminants in a soil enter the human body through the gastrointestinal tract are outlined. The methods available for measuring human exposure using human, animal and validated in-vitro laboratory methods are described ...
Cave, Mark +4 more
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Bioavailability of anthocyanins
Drug Metabolism Reviews, 2014Anthocyanins are a subgroup of flavonoids responsible for the blue, purple, and red color of many fruits, flowers, and leaves. Consumption of foods rich in anthocyanins has been associated with a reduced risk of cardiovascular disease and cancer. The fate of anthocyanins after oral administration follows a unique pattern rather different from those of ...
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Bioavailability of Soil-Bound TCDD: Oral Bioavailability in the Rat
Toxicological Sciences, 1988The implications to the public health of trace amounts of 2,3,7,8-TCDD in the environment are under evaluation by regulatory agencies in the United States and Western Europe. One major consideration in such evaluations is the contribution to human exposure via ingestion of TCDD-contaminated soil.
H, Shu +7 more
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The Bioavailability of Dietary Calcium
Journal of the American College of Nutrition, 2000This update focuses on the bioavailability of dietary calcium for humans. Fundamentals of calcium metabolism, intestinal absorption, urinary excretion and balance are recalled. Dietary factors, especially lactose and other milk components, influencing calcium bioavailability at intestinal and renal levels are reviewed. A critical examination of all the
Guéguen, L., Pointillart, Alain
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Bioavailability of resveratrol
Annals of the New York Academy of Sciences, 2011This paper reviews our current understanding of the absorption, bioavailability, and metabolism of resveratrol, with an emphasis on humans. The oral absorption of resveratrol in humans is about 75% and is thought to occur mainly by transepithelial diffusion. Extensive metabolism in the intestine and liver results in an oral bioavailability considerably
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