Results 151 to 160 of about 191,359 (300)

Genetics of educational resilience after adverse childhood experiences. [PDF]

EBioMedicine
Yang H, Daníelsdóttir HB, Zeng Y, Hou C, Wang H, Hauksdottir A, Thordardottir EB, Tómasson G, Jakobsdóttir J, Aspelund T, Song J, Fang F, Valdimarsdóttir UA, Song H.   +13 more
europepmc   +1 more source

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

Genotype-first approach reveals monogenic lipodystrophy is underdiagnosed, with health and mortality risks. [PDF]

EBioMedicine
Sharp LN, Colclough K, Murray Leech J, Evans AV, Hattersley AT, Weedon MN, Brown RJ, Patel KA.   +7 more
europepmc   +1 more source

Late‐Onset Rheumatoid Arthritis and Air Pollution in the Multiethnic Cohort

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the effects of ambient air pollution on rheumatoid arthritis (RA) incidence in a racially and ethnically diverse population. Methods This analysis included 42,152 California Multiethnic Cohort participants, aged ≥65 years (>70% African American and Latino adults) who were enrolled in the Fee For Service component of Medicare (2001–
Anna H. Wu, Chiuchen Tseng, Song‐Yi Park, Daniel O. Stram, Kami White, Jun Wu, Cheryl Vigen, Veronica W. Setiawan, Xian Yu, Steven Gazal, Christopher Haiman, Lynne Wilkens, Loïc Le Marchand, Iona Cheng, William Stohl   +14 more
wiley   +1 more source

From Biobank to "Bio-Think-Tank": Functional Evolution of UK Biobank in Public Health Policy Making. [PDF]

Public Health Rev
Yin J, Flahault A.
europepmc   +1 more source

Improved Detection of Myositis‐Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison With Line Blot and Conventional Immunoprecipitation

Arthritis &Rheumatology, EarlyView.
Objective Myositis‐specific autoantibodies guide the diagnosis and classification of idiopathic inflammatory myopathies, but current immunoassays vary in accuracy, particularly for autoantibodies associated with interstitial lung disease. To compare the performance of the luciferase immunoprecipitation systems (LIPS) assay with line blot and ...
Peter D. Burbelo, Iago Pinal‐Fernandez, Maria Casal‐Dominguez, Xin Tian, Shijinqiu Gao, Neha Gupta, Eric W. Robbins, John A. Chiorini, Christopher A. Mecoli, Lisa Christopher‐Stine, Livia Casciola‐Rosen, Andrew L. Mammen, Sonye K. Danoff, Anthony F. Suffredini, Julio A. Huapaya   +14 more
wiley   +1 more source

Institutional Biobanking as shared public health infrastructure: a financially sustainable service center model. [PDF]

Front Health Serv
Olson MV.
europepmc   +1 more source

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao, Yash Pershad, J. Brett Heimlich, Michelle Ormseth, C. Michael Stein, Brian Sharber, Caitlyn Vlasschaert, Alexander G. Bick, Robert W. Corty   +8 more
wiley   +1 more source

Hyperthyroidism drives gout risk: A Mendelian randomization observational study. [PDF]

Medicine (Baltimore)
Pan Y, Zhou S, Luo D.
europepmc   +1 more source