Results 281 to 290 of about 220,549 (336)

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Association Between Chronic Kidney Disease and Glaucoma: Results From the Lifelines Cohort Study and UK Biobank. [PDF]

Invest Ophthalmol Vis Sci
Liu W, Guo R, Wang S, Chen Z, Song M, Faro VL, Zhang W, Asefa NG, Eijgelsheim M, Snieder H, Jansonius NM.   +10 more
europepmc   +1 more source

Exploring Uric Acid to HDL Ratio as a Long‐Term Biomarker for Diabetes Mellitus

Journal of Clinical Laboratory Analysis, EarlyView.
This study explores the predictive value of the serum uric acid to HDL cholesterol ratio (UHR) for diabetes mellitus (DM) using data from the decade‐long MASHAD cohort. Elevated UHR levels were significantly associated with increased DM risk, with gender‐specific thresholds identified through ROC analysis. These findings support UHR as a promising long‐
Rana Kolahi, Reza Khademi, Mahboobeh Ghasemzadeh Rahbardar, Niloofar Shabani, Habibollah Esmaily, Nazanin Akbari, Reyhane Alizadeh, Malihehsadat Abedsaeidi, Sara Saffar Soflaei, Majid Ghayour‐Mobarhan   +9 more
wiley   +1 more source

Mediators of the association between psychological distress and mortality in people diagnosed with cancer. [PDF]

Nat Commun
Miller NE, Pentti J, Steptoe A, Kivimaki M, Lally P, Frank P, Fisher A.   +6 more
europepmc   +1 more source

Diagnostic Concordance of Two‐ and Three‐Gene SARS‐CoV‐2 Molecular Assays in Cameroon: Implications for Efficient Pandemic Response in Low‐ and Middle‐Income Countries

Journal of Clinical Laboratory Analysis, EarlyView.
This study assessed the interoperability of DaAn Gene, ThermoFisher, and GeneXpert assays used for COVID‐19 testing in Cameroon. GeneXpert showed higher diagnostic performance over ThermoFisher, with all assays having excellent agreement at high viral loads (CT < 20).
Aurelie Minelle Kengni Ngueko, Sandrine Claire Djupsa Ndjeyep, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Collins Ambe Chenwi, Aude Christelle Ka'e, Yagai Bouba, Jeremiah Efakika Gabisa, Evariste Molimbou, Naomi‐Karell Etame, Tatiana Anim‐Keng Tekoh, Rachel Audrey Nayang Mundo, Pamela Patricia Tueguem, Vincent Kamael Mekel, Hugues Mba, Désiré Takou, Grace Angong Beloumou, Michel Carlos Tommo Tchouaket, Larissa Gaelle Moko Fotso, Derrick Tambe Ayuk, Christian Ngongang Ouankou, Claudia Alteri, Luna Colagrossi, Yap Boum II, Halle Gregory Eddy Ekane, Francesca Ceccherini‐Silberstein, Vittorio Colizzi, Nicaise Ndembi, Alfred K. Njamnshi, Alexis Ndjolo, Carlo‐Federico Perno, Maria‐Mercedes Santoro, Joseph Fokam   +32 more
wiley   +1 more source

Associations between the Mediterranean lifestyle and incident age-related eye diseases: a longitudinal analysis from the UK Biobank. [PDF]

J Glob Health
Li Y, Zhang Y, Wong G, Kam KW, Ho M, Au S, Zhang XJ, Ng MP, Ip P, Young AL, Pang CP, Tham CC, Chen LJ, Yam JC.   +13 more
europepmc   +1 more source

The Genetic Link Between Primary Immune Thrombocytopenia and Depression/Anxiety Disorders: A Two‐Sample Mendelian Randomization Study

Journal of Clinical Laboratory Analysis, EarlyView.
A two‐sample Mendelian randomization study revealed a positive genetic association between primary immune thrombocytopenia (ITP) and major depressive disorder (MDD), but not with anxiety. Results remained consistent across sensitivity and multivariable analyses, indicating that ITP may causally increase susceptibility to depression.
Le Jiang, Ya‐jing Zhao, Shou‐qing Han, Zhen‐yu Yan, Xin‐guang Liu   +4 more
wiley   +1 more source

Complex genetic effects linked to plasma protein abundance in the UK Biobank. [PDF]

Nat Commun
Sigurdsson AI, Gräf JF, Yang Z, Ravn K, Meisner J, Thielemann R, Webel H, Smit RAJ, Niu L, Mann M, FinnGen, Vilhjalmsson B, Neale BM, Holm JC, Ganna A, Hansen T, Loos RJF, Rasmussen S.   +17 more
europepmc   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

JCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson, Ashraf Yahia, Mark J. Taylor, Angelica Ronald, Kristiina Tammimies, Terje Falck‐Ytter   +5 more
wiley   +1 more source

GWAS and Replication Analysis of Apparent Treatment-Resistant Hypertension. [PDF]

Hypertension
Ebinger JE, Kauko A, Vaura F, Hage P, Sundström J, FinnGen, Joung SY, Cheng S, Niiranen TJ.   +8 more
europepmc   +1 more source