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Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease [PDF]
Cell Genomics, 2022 Summary Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry.
Marie-Julie Fave +2 more
exaly +3 more sources
Genotyping and population characteristics of the China Kadoorie Biobank
Cell Genomics, 2023 Summary The China Kadoorie Biobank (CKB) is a population-based prospective cohort of >512,000 adults recruited from 2004 to 2008 from 10 geographically diverse regions across China.
Robin G Walters
exaly +4 more sources
Cell Genomics, 2023 Genome-wide association studies (GWASs) have identified tens of thousands of genetic loci associated with human complex traits. However, the majority of GWASs were conducted in individuals of European ancestries.
Chia-Yen Chen +2 more
exaly +2 more sources
American Journal of Epidemiology, 2017 The UK Biobank cohort is a population-based cohort of 500,000 participants recruited in the United Kingdom (UK) between 2006 and 2010. Approximately 9.2 million individuals aged 40–69 years who lived within 25 miles (40 km) of one of 22 assessment ...
Thomas J Littlejohns +2 more
exaly +2 more sources
A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
Cell, 2018 Norman Sachs +2 more
exaly +2 more sources
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Molecular Biotechnology, 2008
Biobanks, more formally known as biological resource centers (BRCs), form an "unsung" yet critical component of the infrastructures for scientific research, industry and conservation, without which much of the current scientific activity involving microbial cultures and cell-lines would be effectively impossible.
John G, Day, Glyn N, Stacey
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Biobanks, more formally known as biological resource centers (BRCs), form an "unsung" yet critical component of the infrastructures for scientific research, industry and conservation, without which much of the current scientific activity involving microbial cultures and cell-lines would be effectively impossible.
John G, Day, Glyn N, Stacey
openaire +2 more sources
Sustainability in Biobanking: Model of Biobank Graz
Biopreservation and Biobanking, 2015Research infrastructures remain the key for state-of-the-art and successful research. In the last few decades, biobanks have become increasingly important in this field through standardization of biospecimen processing, sample storage, and standardized data management. Research infrastructure in cohort studies and other sample collection activities are
Karine, Sargsyan +8 more
openaire +2 more sources
Biopreservation and Biobanking, 2013
The term “biobank” first appeared in the scientific literature in 1996 and for the next five years was used mainly to describe human population-based biobanks. In recent years, the term has been used in a more general sense and there are currently many different definitions to be found in reports, guidelines and regulatory documents.
Robert, Hewitt, Peter, Watson
openaire +2 more sources
The term “biobank” first appeared in the scientific literature in 1996 and for the next five years was used mainly to describe human population-based biobanks. In recent years, the term has been used in a more general sense and there are currently many different definitions to be found in reports, guidelines and regulatory documents.
Robert, Hewitt, Peter, Watson
openaire +2 more sources
Biobanks and biobank harmonisation
2017Over the past decade and a half, genetic epidemiology has experienced an important shift from family-based studies of genetic linkage to individual-based studies of genetic association (Chapters One-Four). In part, this follows the recognition that if the 'common disease, common variant hypothesis'1-5 is true for at least a proportion of important ...
Burton, P. +4 more
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