Results 311 to 320 of about 171,678 (355)

Whole-genome sequencing of 490,640 UK Biobank participants

Nature
Whole-genome sequencing provides an unbiased and complete view of the human genome and enables the discovery of genetic variation without the technical limitations of other genotyping technologies.
Keren Bjarni V. Liping Jimmy Eleanor Yancy Kousik Zhuoyi Carss Halldorsson Hou Liu Wheeler Lo Kundu Huang L, Keren Bjarni V. Liping Jimmy Eleanor Yancy Kousik Zhuoyi Carss Halldorsson Hou Liu Wheeler Lo Kundu Huang L, K. Carss, B. Halldórsson, Liping Hou, Jimmy Liu, Eleanor Wheeler, Yancy Lo, Kousik Kundu, Zhuoyi Huang, Ben Lacey, R. Dhindsa, D. Rajan, Jelena Randjelovic, N. Marriott, C. Scott, A. Yavuz, I. Johnston, Trevor Howe, Mary Helen Black, K. Stefánsson, R. Scott, S. Petrovski, Shuwei Li, A. Cortes, Fengyuan Quanli Oliver S. Sri V. V. Carolina Kieren Peter H Hu Wang Burren Deevi Haefliger Lythgow Maccallum M, Fengyuan Hu, Quanli Wang, O. Burren, S. Deevi, C. Haefliger, Kieren T. Lythgow, P. Maccallum, K. Megy, J. Mitchell, Sean O’Dell, A. O’Neill, Katherine R. Smith, Haeyam Taiy, M. Pangalos, Ruth E. March, S. Wasilewski, Hannes P. Kristjan H. S. Hannes Ogmundur Aron Nokkvi Svan Eggertsson Moore Hauswedell Eiriksson Skaftason Gi, H. Eggertsson, K. Moore, Hannes Hauswedell, Ogmundur Eiriksson, Aron Skaftason, Nokkvi Gislason, Svanhvít Sigurjónsdóttir, M. O. Ulfarsson, G. Pálsson, Marteinn Þ Hardarson, A. Oddsson, B. Jensson, Snaedis Kristmundsdottir, Brynja D. Sigurpálsdóttir, Olafur A. Stefansson, Doruk Beyter, Guillaume Holley, Vinicius Tragante, A. Gylfason, Pall I. Olason, Florian Zink, M. Ásgeirsdóttir, Sverrir T. Sverrisson, Brynjar Sigurdsson, S. A. Gudjonsson, G. Sigurdsson, G. Halldorsson, G. Sveinbjornsson, U. Styrkársdóttir, Droplaug N. Magnúsdóttir, S. Snorradóttir, Kari Kristinsson, Emilia Sobech, G. Thorleifsson, F. Jónsson, P. Melsted, I. Jónsdóttir, T. Rafnar, H. Hólm, H. Stefánsson, J. Saemundsdottir, D. Gudbjartsson, Olafur T. Magnusson, G. Másson, U. Thorsteinsdóttir, Agnar Helgason, Hákon Jónsson, P. Sulem, Jatin Tom G. Laurence Chloe Dongjing Patrick Mariana Dan Sandhuria Richardson Howe Robins Liu Albers Pereir, Jatin Sandhuria, T. G. Richardson, Laurence Howe, Chloe Robins, Dongjing Liu, Patrick K. Albers, M. Pereira, Daniel Seaton, Yury S. Aulchenko, J. Whittaker, Manolis Dermitzakis, Toby Johnson, J. Davitte, E. Ingelsson, Julio Yanfei Alexander H. Evan H. Elisabeth Abolfazl Doo Molineros Zhang Li Baugh Mlynarski Torshizi Abdel-, J. Molineros, Yanfei Zhang, Alexander Li, E. Baugh, E. Mlynarski, A. D. Torshizi, Gamal A. Abdel-Azim, Brian Mautz, Karen Y. He, Jingyue Xi, Shirley Nieves-Rodriguez, Asif Khan, Songjun Xu, Xingjun Liu, Brice A. J. Sarver, Dongnhu T. Truong, M. Temanni, Christopher D. Whelan, Letizia Goretti, Najat Khan, B. Fraile, Tommaso Mansi, Gunaretnam Rajagopal, Shaheen Siobhan Robert Daniel Tristram Adrian Richard Mari Akhtar Austin-Guest Barber Barrett Bellerby Clarke, Shaheen Akhtar, Siobhan Austin-Guest, Robert Barber, D. Barrett, Tristram Bellerby, Adrian Clarke, Richard Clark, M. Coppola, Linda Cornwell, Abby Crackett, Josephine Dawson, Callum Day, A. Dove, J. Durham, Robert Fairweather, Marcella Ferrero, M. Fenton, Howerd Fordham, A. Fraser, Paul Heath, E. Heron, Gary Hornett, Lena Hughes-Hallett, David K. Jackson, Alexander Jakubowski Smith, Adam Laverack, Ka-ho. Law, Steven Leonard, Kevin Lewis, J. Liddle, Alice Lindsell, Sally Linsdell, J. Lovell, James Mack, Henry Mallalieu, I. Mamun, Ana Monteiro, L. Morrow, Barbora Pardubska, Alex Popov, Lisa Sloper, Janet Squares, Ian R. Still, O. Taylor, Samuel Taylor, Jaime M. Tovar Corona, Elliott Trigg, Valerie E. Vancollie, Paul Voak, Danni Weldon, Alan Wells, E. Wells, Mia Williams, Sean Wright, Nevena Miletić, Lea Lenhardt Ackovic, Marijeta S. Slavkovic-Ilic, Mladen Lazarevic, Louise Aigrain, N. Redshaw, Michael A. Quail, Lesley M Shirley, Scott A. J. Thurston, Peter Ellis, Laura Grout, Nathalie Smerdon, Emma V. Gray, Richard Rance, Cordelia Langford, Rory Mark Naomi Jonathan Simon Mahesh Caroline Lucy Sam Collins Effingham Allen Sellors Sheard Pancholi Cl, R. Collins, Mark Effingham, Naomi Allen, J. Sellors, Simon Sheard, Mahesh Pancholi, C. Clark, L. Burkitt-Gray, Samantha Welsh, Daniel Fry, R. Watson, Lauren Carson, A. Young, Rami Ole Mehio Schulz-Trieglaff, Rami Mehio, Ole Schulz-Trieglaff   +216 more
semanticscholar   +1 more source

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

Nature Genetics
Large biobanks, such as the UK Biobank (UKB), enable massive phenome by genome-wide association studies that elucidate genetic etiology of complex traits.
K. Karczewski, Rahul Gupta, M. Kanai, Wenhan Lu, K. Tsuo, Ying Wang, R. Walters, Patrick Turley, Shawneequa Callier, Nirav N. Shah, N. Baya, Duncan S. Palmer, J. Goldstein, G. Sarma, M. Solomonson, N. Cheng, S. Bryant, C. Churchhouse, C. Cusick, T. Poterba, J. Compitello, D. King, Wei Zhou, C. Seed, H. Finucane, M. Daly, B. Neale, E. Atkinson, Alicia R. Martin   +28 more
semanticscholar   +1 more source

Biobanking for epidemiology

Public Health, 2012
Biobanks are a key resource in unravelling the association between genetic background, lifestyle and environmental determinants of the incidence, natural course and treatment response for various complex diseases and health traits. Biobanks are goldmines for epidemiological research, provided that they are set up properly, enable multicentre ...
openaire   +2 more sources

Racial Differences and Similarities in Atrial Fibrillation Epidemiology, Risk Factors in UK Biobank and Korean NHIS-HEALS cohort studies.

Heart Rhythm
BACKGROUND The increasing prevalence of atrial fibrillation (AF) requires efforts to understand racial differences in disease distribution and risk factors.
Moon-Hyun Kim, Pil-Sung Yang, Daehoon Kim, E. Jang, H. Yu, Tae‐Hoon Kim, J. Sung, H. Pak, Moon‐Hyoung Lee, G. Y. Lip, B. Joung   +10 more
semanticscholar   +1 more source

Biobanking and Pharmacogenomics

Pharmacogenomics, 2010
The study of genetic determinants underlying drug outcome is rapidly advancing. Initial success was realized within the context of candidate pharmacokinetic genes and serious adverse drug reactions, particularly for drugs with narrow therapeutic indices.
Catherine A, McCarty, Russell A, Wilke
openaire   +2 more sources

Biobanking in Estonia

Journal of Law, Medicine & Ethics, 2016
Estonia is a democratic, parliamentary republic with a health care system that is built on the principle of compulsory, solidarity-based insurance and the all-round availability of services of private service providers. Estonia has specific biobank legislation as well as oversight via data protection laws.
openaire   +2 more sources

Sustainability in Biobanking

Biopreservation and Biobanking, 2014
Tight economic realities in clinical and research operations have spurred the need to re-examine financial models that support the infrastructure of biobanking. Finding ways to streamline operations, trim costs, and become more conscious of the carbon footprint of biobank operations has made ‘‘sustainability’’ a well-used buzzword of our time.
Daniel, Simeon-Dubach, Marianne K, Henderson   +1 more
openaire   +2 more sources

Nursing and Biobanking

2015
Nurses are a pivotal component of the translational research movement and apply scientific discoveries to the healthcare and clinical practice fields. Biobanking is also an important factor in furthering translational research by providing biospecimens and related clinical data to the research community.
Jennifer, Sanner, Erica, Yu, Krystle, Nomie   +2 more
openaire   +2 more sources

Human Biobanks:

2011
The chapter presents a careful comparative study on ethical and legal aspects of human biobanks both in Europe and elsewhere. The rapid expansion of human DNA sampling and data collection has taken place in the last few years, but the legal and ethical perception of this situation looks very different in European countries and beyond.
openaire   +1 more source

China Biobanking

2015
Biobanks are playing increasingly important roles in clinical and translational research nowadays. China, as a country with the largest population and abundant clinical resources, attaches great importance to the development of biobanks. In recent years, with the increasing support from the Chinese government, biobanks are blooming across the country ...
Yong, Zhang, Qiyuan, Li, Xian, Wang, Xiaolin, Zhou   +3 more
openaire   +2 more sources