Results 151 to 160 of about 13,313 (262)

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat, Maria del Carmen Zamora‐Medina, Sang‐Cheol Bae, Megan R. W. Barber, Ann E. Clarke, Paul R. Fortin, Zahi Touma, Carl A. Laskin, Isabelle Malhamé, Giada Sebastiani, Christine Peschken, Manuel F. Ugarte‐Gil, Alexandra Legge, Sasha Bernatsky, Évelyne Vinet   +14 more
wiley   +1 more source

Navigating tensions between scientific advancement and ethical practice in biobanking: a qualitative study in Japan. [PDF]

Front Genet
Oikawa M, Takimoto Y.
europepmc   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Biobanking knowledge and donation willingness among musculoskeletal patients in England: a multisite cross-sectional study. [PDF]

BMJ Open
Boakye Serebour T, Kerasidou A, Gray N, Griffin XL, Peach C, Singh HP, Wheway K, Ambrosio MDG, Baldwin M, Snelling SJB.   +9 more
europepmc   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

The case for an integrated biobanking initiative in South Asia. [PDF]

Lancet Reg Health Southeast Asia
Salvatore M, Wang Y, Syal P, Wahl B, Parikh H, Deo V, Bhatraju NK, Jayaweera K, Rana N, Ranjan R, Jehan F, Yusuf A, Adapa K, Duggal M, Agrawal A, Mukherjee B.   +15 more
europepmc   +1 more source

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

Streamlining protocols for the establishment of a physical biobank of respiratory viruses in the Philippines. [PDF]

J Transl Med
Reyes-Haygood SJ, Rala-Ramos L, Balgos Pada-On JE, Pigao EC, Nicole Perreras MA, Tongol AF, Leon A, Alonzo-Dimamay MT.   +7 more
europepmc   +1 more source

The central biobank and virtual biobank of BIOMARKAPD

Biobanks are important resources for biomarker discovery and assay development. Biomarkers for Alzheimer's and Parkinson's disease (BIOMARKAPD) is a European multicenter study, funded by the EU Joint Programme-Neurodegenerative Disease Research, which aims to improve the clinical use of body fluid markers for the diagnosis and prognosis of Alzheimer's ...
Reijs, Babette L. R., Teunissen, Charlotte E.||, Goncharenko, Nikolai||, Betsou, Fay||, Blennow, Kaj||, Baldeiras, Inês||, Brosseron, Frederic, Cavedo, Enrica||, Fladby, Tormod||, Froelich, Lutz||, Gabryelewicz, Tomasz, Gurvit, Hakan||, Kapaki, Elisabeth N., Koson, Peter, Kulic, Luka, Lehmann, Sylvain||, Lewczuk, Piotr||, Lleó, Alberto||, Maetzler, Walter||, de Mendonça, Alexandre||, Miller, Anne-Marie, Molinuevo, José Luis||, Mollenhauer, Brit||, Parnetti, Lucilla||, Rot, Uroš, Schneider, Anja||, Simonsen, Anja Hviid||, Tagliavini, Fabrizio||, Tsolaki, Magda||, Verbeek, Marcel||, Verhey, Frans, Zboch, Marzena, Winblad, Bengt||, Scheltens, Philip||, Zetterberg, Henrik||, Visser, Pieter Jelle||   +35 more
openaire   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source