Results 201 to 210 of about 61,606 (334)

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

Advancing Wildlife Conservation Through Biobanking in South America. [PDF]

Animals (Basel)
Madelaire CB, Pereira AF, Sestelo AJ, Bom-Conselho AP, Vaj C, Mosalve FC, Brandão-Souza LS, Tavares MR, Rodriguez MD, Restrepo RO, Leite RF, Locatelli Y, Deco-Souza T, Araujo GR.   +13 more
europepmc   +1 more source

A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

Attitudes of blood and plasma donors towards biobanking for longitudinal health research. [PDF]

PLoS One
Joosten KF, van Dammen L, Merz EM, Novotný VMJ, Thijssen-Timmer DC, van den Hurk K.   +5 more
europepmc   +1 more source

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

Building global research equity through lung organoids: a prerequisite for the next respiratory pandemic. [PDF]

Front Med (Lausanne)
Hossain MK, Kim HR.
europepmc   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Documenting participant Consent in archival records: Aligning yesterday's practices with today's processes. [PDF]

HRB Open Res
Kuriakose N, Annuk H, Duggan S, Carroll O, Kerin M, Miller N.   +5 more
europepmc   +1 more source

Brain Health for Children

Brain Health, EarlyView.
ABSTRACT The World Health Organization (WHO) defines brain health as the maintenance of optimal brain integrity, good mental state, and cognitive function without significant neuropsychiatric disease. Early childhood is a critical period for brain development, which were influenced by early experiences, nutrition, and environmental factors. Disruptions
Yu Ma, Wenjuan Ma, Yue Jiang, Weiyi Chen, Yuanfeng Zhou, Yi Wang   +5 more
wiley   +1 more source

Developing biobanking processes for Alzheimer's disease and related dementia research in Africa: Experience from the Recruitment and Retention for Alzheimer's Disease Diversity in the Alzheimer's Disease Sequencing Project (READD-ADSP). [PDF]

Alzheimers Dement
Akinwande KS, Whitehead P, Diala S, Coker M, Adams LD, Ogunronbi M, Balogun O, Boateng R, Kudzi W, Falayi A, Nyamai PK, Novela CF, Kelemu T, Abdulraheem JY, Adeleye O, Anyanwu RA, Ankamah J, Emmanuel BO, Imoh LC, Doku-Agama WA, Kumburu H, Kamulegeya R, Ige KB, Famuyiwa OO, Ogunde G, Ejimkonye FC, Akinyemi J, Cuccaro M, Mena P, Ogbole G, Elugbadebo O, Farombi T, Nichols M, Adeniyi S, Uthman M, Musyimi C, Mutiso V, Wahab K, Osaigbovo G, Nwazor E, Osemwegie N, Nwani P, Ogundele AT, Olowoyo P, Iwuozo EU, Mlaki DA, Obiako R, Sarfo F, Akpalu A, Adoukonou T, Ayele BA, Zenebe Y, Lwere K, Damasceno A, Njamnshi AK, Boshe J, Paddick SM, Seshadri S, McCauley J, Walker R, Arulogun O, Okubadejo N, Baiyewu O, Byrd G, Owolabi M, Ndetei D, Kunkle BW, Griswold AJ, Kalaria RN, Vance J, Ogunniyi A, Pericak-Vance M, Akinyemi R.   +72 more
europepmc   +1 more source