Results 51 to 60 of about 26,930 (292)

Consent for the use of human biological samples for biomedical research: a mixed methods study exploring the UK public’s preferences [PDF]

, 2013
OBJECTIVE: A mixed-methods study exploring the UK general public's views towards consent for the use of biosamples for biomedical research.<p></p> SETTING: Cross-sectional population-based focus groups followed by an online survey.<p>&
Clotworthy, M, Corfield, J, Hilton, S, Lewis, C, Magee, C, Robertson, MJ, Stubbins, LJ   +6 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Biosafety and Biohazards: Understanding Biosafety Levels and Meeting Safety Requirements of a Biobank. [PDF]

, 2019
When it comes to biobanking and working with different types of laboratory specimens, it is important to understand potential biohazards to ensure safety of the operator and laboratory personnel.
Gosa, Laura, Nathanson, David A, Ta, Lisa   +2 more
core   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Qualitative study of knowledge and attitudes to biobanking among lay persons in Nigeria

BMC Medical Ethics, 2012
Background Interest in biobanking for collection of specimens for non-communicable diseases research has grown in recent times. This paper explores the perspectives of Nigerians on donation of specimen for the biobanking research. Methods We conducted 16
Igbe Michael A, Adebamowo Clement A
doaj   +1 more source

The Socio-genetic marginalization in Asia programme (SMAP) [PDF]

, 2005
SMAP, the Socio-genetic Marginalization in Asia Programme, which started off in August 2004, is a research programme set up with the support of the Netherlands Science Organisation (NWO), IIAS, and the Amsterdam School for Social Science Research (ASSR).
Sleeboom-Faulkner, Margaret
core  

Dual consent? Donors' and recipients' views about involvement in decision-making on the use of embryos created by gamete donation in research [PDF]

, 2019
Background Reasonable disagreement about the role awarded to gamete donors in decision-making on the use of embryos created by gamete donation (EGDs) for research purposes emphasises the importance of considering the implementation of participatory ...
Baia, I, De Freitas, C., Provoost, Veerle, Samorinha, C., Silva, S.   +4 more
core   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

HPV Testing of Biobanked Liquid-Based Cytology – a Validation Study

The International Journal of Biological Markers, 2016
Introduction The aim of the study was to investigate whether biobanked liquid-based cytology (LBC) vaginal samples could be reanalyzed for the biomarkers HPV DNA and mRNA without loss of sensitivity.
Gabriella Lillsunde Larsson, Mats G. Karlsson, Gisela Helenius   +2 more
doaj   +1 more source

Proceedings of the 3rd Indian Cancer Genome Atlas Conference 2022: Biobanking to Omics: Collecting the Global Experience

JCO Global Oncology, 2023
On January 13th and 14th 2022, the Center for Translational Cancer Research organized the virtual third Indian Cancer Genome Atlas (ICGA) Conference 2022 “Biobanking to Omics – Collecting the Global Experience.” This conference was planned as the ...
Sneha Joshi, Rupa Mishra, Madhura Kulkarni, Devaki A. Kelkar, Keerthi Harikrishnan, Pooja Vaid, Gomathi V, Jisha John, Siddhi Tamhane, Anand Deshpande, Sunil Badve, Chintamani, Ravi Mehrotra, L.S. Shashidhara, Ashutosh Kothari, Chaitanyanand Koppiker   +15 more
doaj   +1 more source