Results 31 to 40 of about 13,313 (262)

Inter- and Intra-Biobank Networks: Classification of Biobanks [PDF]

open access: yesPathobiology, 2010
<i>Background:</i> Many biobanks have struggled to deliver on the high expectations and claims made for them because of insufficient samples, inadequate infrastructure, cost of establishing and maintaining a large enough resource over the long term, and satisfying legal, ethics and governance requirements. Increasingly, networks have formed
Darren, Shickle   +2 more
openaire   +2 more sources

Access to Biobanks: Harmonization Across Biobank Initiatives [PDF]

open access: yesBiopreservation and Biobanking, 2014
The current study investigates whether access arrangements relevant for biobanking contain clear information on key access conditions. It furthermore assesses the extent to which these access conditions are harmonized across biobank initiatives.A comparative analysis was conducted of access arrangements developed by 26 organizations, 36 biobank ...
Michiel, Verlinden   +3 more
openaire   +3 more sources

Determinants of the willingness to participate in biobanking among Malaysian stakeholders in the Klang Valley

open access: yesBMC Medical Research Methodology, 2018
Background The demand in biobanking for the collection and maintenance of biological specimens and personal data from civilians to improve the prevention, diagnosis and treatment of diseases has increased notably. Despite the advancement, certain issues,
Latifah Amin   +3 more
doaj   +1 more source

Human iPSC Reprogramming Success: The Impact of Approaches and Source Materials

open access: yesStem Cells International
Since their discovery, human induced pluripotent stem cells (hiPSCs) have been instrumental in biomedical research, particularly in the fields of disease modelling, drug screening and regenerative therapies.
Tatyana Pozner   +4 more
doaj   +1 more source

Biobanks—A Platform for Scientific and Biomedical Research

open access: yesDiagnostics, 2020
The development of biomedical science requires the creation of biological material collections that allow for the search and discovery of biomarkers for pathological conditions, the identification of new therapeutic targets, and the validation of these ...
Kristina Malsagova   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ethics and biobanks [PDF]

open access: yesBritish Journal of Cancer, 2008
Biobank research has been the focus of great interest of scholars and regulatory bodies who have addressed different ethical issues. On the basis of a review of the literature it may be concluded that, regarding some major themes in this discussion, a consensus seems to emerge on the international scene after the regular exchange of arguments in ...
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Biobanking and consenting to research: a qualitative thematic analysis of young people’s perspectives in the North East of England

open access: yesBMC Medical Ethics, 2023
Background Biobanking biospecimens and consent are common practice in paediatric research. We need to explore children and young people’s (CYP) knowledge and perspectives around the use of and consent to biobanking.
Fabian J. S. van der Velden   +11 more
doaj   +1 more source

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