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Constructing Effective Ethical Frameworks for Biobanking [PDF]
This paper is about the actual and potential development of an ethics that is appropriate to the practices and institutions of biobanking, the question being how best to develop a framework within which the relevant ethical questions are first identified
Widdows, Heather; id_orcid +1 more
core +11 more sources
Pathology and biobanking [PDF]
Biobanks are units where high quality and long-term protection of biomaterials is maintained. This system, in which biological materials and data are systematically recorded and stored, is a unique resource for the study of the pathophysiology of disease, the development of diagnostic biomarkers, and working with human tissues for the potential ...
Kelten Talu, Canan +3 more
openaire +4 more sources
Global Biobank Week: Toward Harmonization in Biobanking [PDF]
Balwir Matharoo-Ball +13 more
core +4 more sources
Analysis of Structural Changes in the Protein near the Phosphorylation Site
Modification of the protein after synthesis (PTM) often affects protein function as supported by numerous studies. However, there is no consensus about the degree of structural protein changes after modification. For phosphorylation of serine, threonine,
Kirill S. Nikolsky +5 more
doaj +1 more source
Molecular Modeling Insights into Upadacitinib Selectivity upon Binding to JAK Protein Family
Rheumatoid arthritis (RA) is a chronic disease characterized by bone joint damage and incapacitation. The mechanism underlying RA pathogenesis is autoimmunity in the connective tissue.
Amir Taldaev +4 more
doaj +1 more source
Biobanks for genomics and genomics for biobanks [PDF]
AbstractBiobanks include biological samples and attached databases. Human biobanks occur in research, technological development and medical activities. Population genomics is highly dependent on the availability of large biobanks. Ethical issues must be considered: protecting the rights of those people whose samples or data are in biobanks (information,
Cambon-Thomsen, Anne +3 more
openaire +5 more sources
Comparison of DNA extraction methods for samples from old blood collections
In this study, DNA was extracted from whole blood which had been collected and stored at -20°C for 5–18 years, with the aim of determining the most suitable commercial DNA extraction kit for this purpose.
Sarah Samut Tagliaferro +3 more
doaj +1 more source
Building Research Support Capacity across Human Health Biobanks during the COVID-19 Pandemic
Human health biobanks are forms of research infrastructure that supply biospecimens and associated data to researchers, and therefore juxtapose the activities of clinical care and biomedical research.
Jennifer A Byrne +6 more
doaj +1 more source
Dried Blood Spot in Laboratory: Directions and Prospects
Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes ...
Kristina Malsagova +5 more
doaj +1 more source
Stakeholder perspectives on the ethico-legal dimensions of biobanking in South Africa
Background Biobanking provides exciting opportunities for research on stored biospecimens. However, these opportunities to advance medical science are fraught with challenges including ethical and legal dilemmas.
Shenuka Singh, Keymanthri Moodley
doaj +1 more source

