Results 181 to 190 of about 32,321 (308)

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

A comprehensive European Colorectal Cancer Cohort dataset. [PDF]

Sci Data
Holub P, Törnwall O, Garcia Alvarez E, Proynova R, Stampe F, Maqsood S, Ataian M, Schlünder I, Carpén O, Meijer G, Nenutil R, Valík D, Parodi B, Hiemstra A, Bierkens M, Castanos-Vélez E, Ückert F, Alexandre D, Vojtíšek O, Bader AL, Simell B, Ahern C, Horvat V, Steinfelder E, Gnocchi M, Moscatelli M, Fürbaß A, Horák J, Frexia F, Mascia C, Sulis A, Delussu G, Del Rio M, Meloni V, Pireddu L, Leo S, Piras ME, Kačenga M, Gofflot S, Mate S, Prokosch HU, Romano P, Pistillo D, Hoffmeister M, Brobeil A, Kugic A, Huppertz B, Paleari V, Müller H, Reihs R, Gemoll T, Bantel Y, Sjöblom T, Kyriacou K, Martino SD, Ciliberto G, Kock-Schoppenhauer AK, Oberländer M, Habermann JK, Husmann G, Edqvist PD, Zlobec I, Berger MD, Boeckmann L, George F, Southerington T, Brucker DP, Faugeras L, Vella J, Felice A, Pace M, Fallerini C, Renieri A, Hadjisavvas A, Sargsyan K, Loizidou MA, Besse-Hammer T, Vogl F, Litton JE, Hummel M, Zatloukal K, Lavitrano M.   +81 more
europepmc   +1 more source

Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the risk of intrahepatic cholestasis of pregnancy (ICP) in azathioprine (AZA)–exposed versus unexposed systemic lupus erythematosus (SLE) pregnancies within the multicenter prospective Lupus in Pregnancy (LEGACY) cohort. Methods LEGACY is conducted at Systemic Lupus International Collaborating Clinics in Canada, South Korea, Peru,
Reem Farhat, Maria del Carmen Zamora‐Medina, Sang‐Cheol Bae, Megan R. W. Barber, Ann E. Clarke, Paul R. Fortin, Zahi Touma, Carl A. Laskin, Isabelle Malhamé, Giada Sebastiani, Christine Peschken, Manuel F. Ugarte‐Gil, Alexandra Legge, Sasha Bernatsky, Évelyne Vinet   +14 more
wiley   +1 more source

Ethical navigation of biobanking establishment in Ukraine: learning from the experience of developing countries. [PDF]

J Med Ethics
Sulaieva ON, Artamonova O, Dudin O, Semikov R, Urakov D, Zakharash Y, Kacharian A, Strilka V, Mykhalchuk I, Haidamak O, Serdyukova O, Kobyliak N.   +11 more
europepmc   +1 more source

Essential embryology for the Canadian pathologists’ assistant

Anatomical Sciences Education, EarlyView.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci, William Tsui, Fang‐I Lu, Avrum I. Gotlieb, Danielle C. Bentley   +4 more
wiley   +1 more source

Analysis of Single Particles of Amyloid Beta and α‐Synuclein With Seeded Amplification for the Diagnosis of Alzheimer's and Parkinson's Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala, Marlene Pils, Oliver Bannach, Gültekin Tamgüney, Detlev Riesner   +4 more
wiley   +1 more source

From Biobank to "Bio-Think-Tank": Functional Evolution of UK Biobank in Public Health Policy Making. [PDF]

Public Health Rev
Yin J, Flahault A.
europepmc   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Correction: Phage biobanks as enabling infrastructure for precision phage therapy in the era of antimicrobial resistance. [PDF]

Front Antibiot
Topa-Pila P, Morales KY, Palacios-Mora DP, Flores-Hernández C, Altamirano-Cisneros A, Gavilanes JM, Villacís-López K, Arancibia M, Mora-Domínguez J, Calero-Cáceres W.   +9 more
europepmc   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source