Results 191 to 200 of about 32,636 (240)

Conserved Asp233–Asp246 hydrogen bond modulates active site dynamics in class A β‐lactamases

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Rigid enzymes catalyze chemical reactions by stabilizing the transition state through a specific conformation. Catalytic residues are precisely positioned, and enzyme dynamics are kept to a minimum. It is thought that conserved residues around the active site (second‐shell residues) play a crucial role in positioning catalytic residues. Asp233
Cristina V. Lopez‐Gallego, Monika Timmer, Jocelyne Vreede, Marcellus Ubbink   +3 more
wiley   +1 more source

Metal-Organic Framework-Gated Biocatalysis Enables Triggered Depolymerization of Melt-Processed Polyesters. [PDF]

Angew Chem Int Ed Engl
Cui S, Tian J, Zhu M, Liu Z, Cao Y, Liu Y, Feng Y, Xu W, Lai W, Yang H, Xu J, Guo B, Qiu L, Yang Z, Falcaro P, Ge J.   +15 more
europepmc   +1 more source

Symmetry‐Guided Optical Control of Dynamic 1D Protein Self‐Assembly and Precise In Vitro Initiation of Biomolecular Condensation

Small, Volume 22, Issue 58, 16 October 2026.
A photoreversible 1D protein assembly has been developed by utilizing symmetry matching between StrepTactin and photoswitchable Dronpa145N. The light‐induced modulation of oligomerization allows for precise control over protein connectivity and valency.
Jangwon Bae, Yongwon Jung
wiley   +1 more source

Correction: The PurR family transcriptional regulator promotes butenyl-spinosyn production in Saccharopolyspora pogona. [PDF]

Appl Microbiol Biotechnol
Li X, Wang J, Su C, Guo C, Xu Z, Wang K, Pang J, Lv B, Wang C, Li C.   +9 more
europepmc   +1 more source

Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior

Small Structures, Volume 7, Issue 10, October 2026.
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam, Lorenzo Travaglini, Yun X. Chen, Dominic J. Glover   +3 more
wiley   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

Cell Proliferation, Volume 59, Issue 10, October 2026.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang, Xingjie Hu, Jinli Sun, Min Yin, Nan Chen   +4 more
wiley   +1 more source

Plastics and Bioplastics End of Life: A Biocatalytic Perspective. [PDF]

Microb Biotechnol
de Eugenio LI, Pardo I, Prieto MA.
europepmc   +1 more source

Pepper RING‐type E3 ligase, CaANKR1, negatively regulates drought tolerance by modulating CaMAPK1 stability

The Plant Journal, Volume 128, Issue 1, October 2026.
SUMMARY Drought stress severely restricts plant growth and productivity, and abscisic acid (ABA)–mediated signaling plays a central role in coordinating adaptive responses to water deficit. Mitogen‐activated protein kinase (MAPK) cascades are widely involved in plant stress signaling; however, the ubiquitin‐mediated regulation of MAPK stability during ...
Junyoung Cho, Chae Woo Lim, Bomyeon Yun, Dae Sung Kim, Sung Chul Lee   +4 more
wiley   +1 more source